Off-target herbicide movement onto rice is an annual problem in rice-producing areas within Mississippi. In Mississippi, rice is routinely drill‐seeded in April to early May. Because these dates often coincide with preplant and/or preemergence (PRE) herbicide applications to corn (Zea mays L.), cotton (Gossypium hirsutum L.), and soybean [Glycine max (L.) Merr.], drift onto neighboring rice crops is likely to occur. Although the effects of off-target movement of paraquat on rice may not be visibly apparent, the potential effect on rough rice yield could be detrimental. Field research was conducted at the Delta Research and Extension Center in Stoneville, MS, in 2019, 2020, and 2021 to characterize rice response to exposure to a range of sub-lethal concentrations of paraquat during the vegetative and reproductive growth phases. Other field experiments characterized rice response to exposure to a sub-lethal concentration of paraquat at different stages of reproductive growth. A final field experiment evaluated rice response and barnyardgrass control with labeled herbicides after exposure to a sub-lethal concentration of paraquat.