Since the founding of the PRC to the present, the period was due to the transitions in political and economic institutional factors made the differences of the developmental pattern of China¡¦s regional economy, and the development of regional economy become more and more diverse with China expanded the extent of the Open Door Policy. In particular, the founding of the Southern-West Regional Economic Cooperation is the breakthrough of the developmental pattern of China¡¦s regional economy after China¡¦s Decentralization Policy. Thus, the research focuses on analyzing the development of the Southern-West Regional Economic Cooperation to treat about the developmental pattern of China¡¦s regional economy. The research uses the systematic analyzing process (Input-output analysis) to treat about the building and development of the economic cooperation from three systematic levels of national, regional and provincial respectively. The input factors of the research focuses on national policy, it includes China¡¦s foreign trade policy, foreign direct investment policy and regional economic development policy respectively. It is treated about how the factors influenced the development of China¡¦s regional economy in Chapter Three? The output factors are treated about how does the building and development of the economic cooperation in Chapter Four and Five? The feedback and revision of the research treat about how to improve the derivational problems through the collaboration with GMS in Chapter Six? Finally, Chapter Seven treats about what does the effects and findings to the present developmental pattern of China¡¦s regional economy through analyzing the development of the economic cooperation?