The major factor for permitting different gold mining leases and enhancing the mining industry in Ghana was to pull in more assets in the nation to enhance the financial fortunes and to lessen the disturbing rate of joblessness. Despite the positive commitment of mining to the nation's economy, there are negative impacts on the ecosystems particularly at the various mining territories in the country. The aim of this study is to evaluate and compare how mining activities in Obuasi municipality and Czech Republic influences the zone's ecosystem and to discover more logical measures to limit such impacts. The quantitative method of data analysis was used in this study through the mean and standard deviation methods while data analyzed were presented using statistical tools such as tables and percentages. The results obtained revealed that mining activities affect all aspects of the ecosystem including water quality, vegetation, soil, landscape as a whole, as well as socio-economic life of the inhabitants within and around the mining communities.