Tobacco use among people with mental illness remain a significant problem in the western United States. At the project site, there is widespread tobacco use among patients with mental illness and lack of training for nurses to address the issue. The purpose of this project was to educate nurses working in the acute psychiatric setting about evidence-based tobacco treatment interventions. The practice-focused question addressed whether a tobacco education program would increase nurses' knowledge, confidence, and skills to provide tobacco treatment interventions to patients with a mental illness. Self-determination theory and the transtheoretical model of change provided the theoretical framework for the project. Evidence was obtained from a comprehensive literature search. The Psychiatry RX for Change education modules were used to implement the education intervention. Nine participants completed pre- and post-test knowledge-based questionnaires and the Skills and Confidence for Smoking Cessation Tool survey. Results from GraphPad t-test analysis indicated a statistically significant increase in perceived knowledge, skills, and confidence among nurses related to tobacco cessation treatment. The mean knowledge pre-test scores were 10.3 and the mean for the post-test score was 14.7. The mean on the pre-survey scores for the nine confidence questions was 16, and the mean on the postscores was 23. The mean obtained on pre-survey scores for the six skills questions was 11.0, and the mean obtained on the post-survey was 18.0. Findings support the use of tobacco education for nurses to improve tobacco treatment offered to patients. The implications of the project for positive social change are that results may be used to improve the quality of life and health outcomes for the patient population.