The purpose of the present study was to determine: (1) that dental office personnel would be exposed to more toxic chemicals in the workplace than the non-dental office controls; (2) that exposure should lead to a reduction in the efficiency of the immune system in the individuals in the dental office; and (3) the immunological deficit should manifest itself in psychological and/or physiological pathology as measured on the Profile of Mood States (POMS) and Bender Gestalt.