Global ETD Search

141	Molecular cloning and characterization of important stress and redox regulatory genes from Hydra vulgaris Dash, Bhagirathi, January 1900 (has links) Thesis (Ph. D.)--Texas A&M University, 2005. / "Major Subject: Toxicology" Title from author supplied metadata (automated record created on Apr. 27, 2007.) Vita. Abstract. Includes bibliographical references. Major Toxicology
142	Astrocyte-derived nitric oxide in manganese neurotoxicity from cellular and molecular mechanisms underlying selective neuronal vulnerability in the basal ganglia to potential therapeutic modalities / Liu, Xuhong, January 1900 (has links) Thesis (Ph. D.)--Texas A&M University, 2005. / "Major Subject: Toxicology" Title from author supplied metadata (automated record created on Apr. 27, 2007.) Vita. Abstract. Includes bibliographical references. Major Toxicology
143	Identification and molecular characterization of novel genomic targets in oxidant-induced vascular injury Partridge, Charles Randal, January 1900 (has links) Thesis (Ph. D.)--Texas A&M University, 2005. / "Major Subject: Toxicology" Title from author supplied metadata (automated record created on Apr. 27, 2007.) Vita. Abstract. Includes bibliographical references. Major Toxicology
144	A study of the toxicology of five arthropods with possibilities as new homoeopathic remedies Bayer, Phillip Richard 05 September 2008 (has links) Dr. P.S. Bayliss Dr. M.R. Moiloa Homeopathy Toxicology
145	Pharmaceutical applications and toxicity of extracted alkenones from marine Isochrysis algae McIntosh, Kyle Douglas 05 September 2019 (has links) No description available. Toxicology Pharmacology
146	Bioassay of insecticide residues in soils. Ilnytzky, Steven. January 1969 (has links) No description available. Insecticides -- Toxicology
147	The Effects of Benzyl Alcohol on Developing Zebrafish (Danio rerio) Schnapp, Alaina M. 20 May 2013 (has links) No description available. Pharmacology Toxicology
148	Glutamate Transporter 1 and Cystine-Glutamate Antiporter as Potential Targets for Attenuating Alcohol Consumption in Male P Rats Aal-Aaboda, Munaf Sabah 22 September 2014 (has links) No description available. Pharmacology Toxicology
149	Effects of Beta-Lactam Antibiotics on Cystine /Glutamate Exchanger Transporter and Glutamate Transporter 1 Isoforms as well as Ethanol Drinking Behavior in Male P Rats Alasmari, Fawaz Fayez January 2015 (has links) No description available. Pharmacology Toxicology
150	Metabolism and bioactivation of 1,2,3-trichloropropane (TCP). Weber, Gregory Louis. January 1991 (has links) 1,2,3-Trichloropropane (TCP) causes rat hepatic DNA damage in the form of DNA single strand breaks. This damage was dose and time dependent. In vivo ¹⁴C-TCP equivalents covalently bound to hepatic protein, RNA and DNA. Glutathione depletion with L-buthionine-(R,S)-sulfoximine increased binding to protein by 342% while it decreased binding to DNA by 56%. The in vivo binding data suggest a dual role for glutathione in the bioactivation of TCP. In vitro rat hepatic microsomes activated TCP to species which covalently bound to microsomal protein. Rat liver microsomes also bioactivated TCP to the direct acting mutagen 1,3-dichloroacetone. 1,3-Dichloroacetone was identified as the major microsomal protein binding species through conjugation with N-acetylcysteine to form 1,3-(2-propanone)-bis-S-(N-acetylcysteine) which accounted for 87% of all TCP microsomal metabolism. These findings support a role for 1,3-dichloroacetone as a mutagenic metabolite of TCP. Carbon-13 nuclear magnetic resonance was used to identify directly the urinary metabolite of ¹³C₃-TCP (99 atom % enrichment). Urine was investigated directly using proton-decoupled ¹³C and two-dimensional homonuclear correlated nuclear magnetic resonance spectroscopy. Spectral shifts have been assigned to N-acetyl-S-(2-hydroxy-3-chloropropyl)cysteine, 1,3-(2-propanol)-bis-S-(N-acetylcysteine), N-acetyl-S-(2-hydroxy-2-carboxyethyl)cysteine, 2,3-dichloropropionic acid, 2-chloroethanol, ethylene glycol and oxalic acid by comparison to spectra of authentic standards. No unchanged TCP was detected. From the results obtained it is concluded that metabolism of TCP by cytochromes P450 and by glutathione conjugation can result in the formation of reactive metabolites of TCP which may be responsible for TCP genotoxicity. Dissertations, Academic Genetic toxicology Toxicology.

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