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  • About
  • The Global ETD Search service is a free service for researchers to find electronic theses and dissertations. This service is provided by the Networked Digital Library of Theses and Dissertations.
    Our metadata is collected from universities around the world. If you manage a university/consortium/country archive and want to be added, details can be found on the NDLTD website.

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Spelling suggestions: "subject:"type ATPas""

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Monte Carlo Simulations of Oligomerized Na+,K+-ATPase / Monte Carlo simulering av oligomeriserat Na+,K+-ATPas

Jönsson, Jakob January 2022 (has links)
Na+,K+-ATPase (NKA) is a membrane protein which assists in maintaining the electrochemical potential across the cell membrane. It has been suggested that the oligomerization of NKA may play a role in intracellular regulation of NKA activity. Monte Carlo simulations of NKA on a picket-fence membrane model were performed to examine if clustering has an effect on NKA efficiency. The results show that for a simple model of NKA interaction, oligomerization may drastically reduce the efficiency as measured in ATP turnover rate. Introducing a rate limit shows a clear separation between monomers and higher levels of oligomerization.
biophysics
p-type ATPase
enzyme activity
simulation
biofysi
p-typ ATPas
enzym aktivitet
simulering
Physical Sciences
Fysik

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