The increasing demand for efficient cancer treatment inspired the researchers for new investigations about an alternative treatment of cancer. Microwave ablation is the newest ablation technique to cure cancer. This method is minimally noninvasive and inexpensive compared to the other methods. However, current microwave ablation systems suffer due to narrowband nature of the antenna (dipole or slot) placed at the tip of the probe. Therefore, this study developed an ultra-wideband ablation probe that operates from 300MHz to 10 GHz. For this purpose, a small wideband antenna is designed to place at the tip of the probe and fabricated. These probes are tested at ISM frequencies (2.4 GHz and 5.8GHz) in skin mimicking gels and pig liver. Microwave ablation probe design, simulation results, and experiment results are provided in this thesis.