The objective of this research was to map and determine the updip limit and locate reservoir potential of the Smackover Formation in southeast-central Mississippi. This subsurface study was conducted using well log correlation and analysis, structure top and isopach thickness mapping, 2-D seismic analysis, and core descriptions. The conclusions from the study led to an alternate interpretation of the Smackover updip limit affected by basement paleotopography in a possible ridge-valley complex similar to south Alabama based on evidence from Smackover isopach thickness, structure top map of a Pre-Smackover surface that represents underlying formations, and 2-D seismic analysis that agreed with the isopach pinch out. Evidence from two core observations from in the updip and downdip area revealed oomoldic porosity and dolomite lithologies with decreasing porosity and connectivity updip. Strong diagenetic features with no visible porosity were present in some core sections. Analysis to determine reservoir-grade porosity updip would be necessary.