Global ETD Search

1	Targeting uracil exclusion mechanisms for development of anti-viral and anti-cancer therapies Studebaker, Adam W., January 2003 (has links) Thesis (Ph. D.)--Ohio State University, 2003. / Title from first page of PDF file. Document formatted into pages; contains xiii, 210 p.; also includes graphics (some col.). Includes bibliographical references (p. 174-210). Available online via OhioLINK's ETD Center Uracil.
2	Study on yeast enzymes Urc1p and Urc4p in a novel uracil catabolism pathway (URC) Kandasamy, Dineshkumar January 2012 (has links) Purine and pyrimidine bases are the central precursors of DNA and RNA and theirintracellular concentration is balanced by three pathways- de novo, salvage and catabolicpathways. Uracil catabolism pathway has been found in several bacteria and in some fungi(including yeast). Seven genes, URC1-7 have been found to be involved in this novelpathway. There are two “unknown genes” in the yeast Lachancea (Saccharomyces) kluyveri,namelyURC1 and URC4, which play a central role in this pathway and their exact functionremains a mystery.In this project, two S. kluyveri genes, URC1&URC4, were over-expressed in the bacterialsystem and successfully purified. Our preliminary functional assay showed that uridinemonophosphate (UMP) is a likely substrate for Urc1p at pH7, 25ºC. It was shown clearly thatboth uracil and uridine were not the substrate for Urc1p. We tried to phosphorylatechemically synthesized ribosylurea using Drosophila melanogaster deoxyribonucleosidekinase and compared the activity between phosphorylated and non- phosphorylated RU atdifferent conditions. Phosphorylated ribosylurea seemed to be a likely substrate for Urc4p atpH7, 37ºC. Keywords: Uridine monophosphate (UMP), ribosylurea (RU), uracil catabolism. Uracil catabolism
3	Studies of genomic uracil and its excision Kemmerich, Kristin January 2012 (has links) No description available. 610 Uracil
4	On the biosynthesis of nucleic acid pyrimidines via the uracil pathway / Sköld, Ola. January 1960 (has links) Thesis (doctoral)--Karolinska Institutet. Pyrimidines Uracil
5	Mechanistic and synthetic aspects of the annelation reaction of benzocyclobutenedione monoketals with vinyllithiums ; synthetic studies of dihydrouracils / Spangler, Lori A. (Lori Ann) January 1984 (has links) No description available. Chemistry Uracil
6	Uracil-DNA glycosylase inhibitor protein : role of carboxylic acid residues and use for measuring the fidelity of uracil-excision DNA repair synthesis in human cell extracts Sanderson, Russell J. 23 September 1998 (has links) Graduation date: 1999 Uracil DNA repair
7	A study of some effects of 5-fluorouracil and 5-fluoroorotic acid on the the soluble ribonucleic acid of rat liver Wagner, Nancy J. January 1962 (has links) Thesis (M.S.)--University of Wisconsin--Madison, 1962. / Typescript. eContent provider-neutral record in process. Description based on print version record. Includes bibliographical references (leaves 57-66). Nucleic acids. Liver. Uracil.
8	Studies of synthetic drugs I. Partial reduction of some alkyl quaternary salts of pyridine and quinoline carbonamides. II. Studies toward the synthesis of 4-methyl-5, 5-dialkyluracil ... Ma, T. S. January 1940 (has links) Thesis (Ph. D.)--University of Chicago, 1938. / Lithoprinted. "Private edition, distributed by the University of Chicago libraries, Chicago, Illinois." Includes bibliographical references. Pyridine. Amides. Uracil.
9	Effect of 5-Fluorouracil on the electrolyte and water composition of rat tissue Young, Charles William, January 1968 (has links) Thesis (M.S.)--University of Wisconsin--Madison, 1968. / eContent provider-neutral record in process. Description based on print version record. Includes bibliographical references. Uracil. Rats. Tissues.
10	A cytological analysis of the antimetabolite activity of 5-hydroxyuracil in Vicia faba roots Schreiber, Richard William, January 1956 (has links) Thesis (Ph. D.)--University of Wisconsin--Madison, 1956. / Typescript. Vita. eContent provider-neutral record in process. Description based on print version record. Includes bibliographical references (leaves 53-56). Antimetabolites. Cell division. Uracil.

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