111 |
Developing a Model for Bacterial Kidney Disease in the Zebrafish, Danio rerioHulbig, Veronica A. January 2010 (has links) (PDF)
No description available.
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112 |
Characterization of calcium signals during the blastula period of zebrafish (danio rerio) embryogenesis /Ma, Leung Hang. January 2007 (has links)
Thesis (Ph.D.)--Hong Kong University of Science and Technology, 2007. / Includes bibliographical references (leaves 213-239). Also available in electronic version.
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113 |
Cellular behaviors regulating tangential migration of facial branchiomotor neurons in the zebrafish embryoSawant, Anagha. Chandrasekhar, Anand, January 2009 (has links)
The entire thesis text is included in the research.pdf file; the official abstract appears in the short.pdf file; a non-technical public abstract appears in the public.pdf file. Title from PDF of title page (University of Missouri--Columbia, viewed on January 20, 2010). Thesis advisor: Dr. Anand Chandrasekhar. Includes bibliographical references.
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114 |
The functional roles of retinal homeobox genes in zebrafish retinal development and an introduction to silica nanomaterial toxicity in zebrafish embryos /Nelson, Steve M. January 1900 (has links)
Thesis (Ph. D., Neuroscience)--University of Idaho, October 2009. / Major professor: Deborah L. Stenkamp. Includes bibliographical references. Also available online (PDF file) by subscription or by purchasing the individual file.
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115 |
Experience-dependent gene expression for learned vocal behavior in the zebra finch songbirdWhitney, Osceola. Johnson, Frank. January 2004 (has links)
Thesis (Ph. D.)--Florida State University, 2004. / Advisor: Dr. Frank Johnson, Florida State University, College of Arts and Sciences, Department of Psychology. Title and description from dissertation home page (viewed June 16, 2004). Includes bibliographical references.
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116 |
The role of intra- and intercellular Ca[superscript]2+ transients in the differentiation of enveloping layer cells during the blastula period of zebrafish (danio rerio) development /Zhang, Jiao. January 2009 (has links)
Includes bibliographical references (p. 85-99).
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117 |
Cell behaviors driving convergence and extension of the dorsal mesoderm of zebrafish /Glickman, Nathalia S., January 2000 (has links)
Thesis (Ph. D.)--University of Oregon, 2000. / Typescript. Includes vita and abstract. Includes bibliographical references (leaves 106-112). Also available for download via the World Wide Web; free to University of Oregon users.
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118 |
Distinctive functions of methionine aminopeptidase II in embryonic hematopoiesis in zebrafish embryosLin, Huichao. January 2009 (has links)
Thesis (M. Phil.)--University of Hong Kong, 2010. / Includes bibliographical references (leaves 96-103). Also available in print.
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119 |
Characterization of sry-related HMG box group F genes in zebrafish hematopoiesisChung, In-shing., 鍾衍盛. January 2010 (has links)
published_or_final_version / Medicine / Doctoral / Doctor of Philosophy
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120 |
The role of the specific aldehyde dehydrogenase (aldh) isoforms in theregulation of embryonic hematopoiesisWong, Sean-man, Natalie., 黃善敏. January 2012 (has links)
Despite recognition of aldehyde dehydrogenase (Aldh) as a surrogate marker in isolating primitive hematopoietic stem and progenitor cells (HSPC) [1], its role in HSPC regulation, particularly during embryonic development, remains unclear. In this study, we examined the role of Aldh during embryonic hematopoiesis in zebrafish, which has emerged as a model for hematopoietic studies. [2]
Wild--?type and transgenic [Tg(gata1:gfp),Tg(fli1:gfp)] zebrafish embryos were microinjected with anti--?sense morpholinos (MO) at 1--?cell to 4--?cell stage and evaluated by morphology, flow cytometry, in situ hybridization (ISH) and Q-RT-PCR. In addition, human CD34+ cells, which were enriched with hematopoietic stem cells (HSC), were isolated from umbilical cord blood samples for analysis of ALDH16A1 expression. It was subsequently compared with CD34- cells which were devoid of HSC activity.
When aldh16a1 was knocked down by anti-sense morpholino (the embryos were referred herewith aldh16a1MO embryos), gene expression associated with erythropoiesis was significantly reduced at 18hpf .(gata1:0.70±0.03fold; p=0.002) (α-embryonic hemoglobin: 0.48±0.04fold; p=0.003) (β-embryonic hemoglobin: 0.56±0.03fold; p=0.001). Angiogenesis was also perturbed at 48 and 72hpf. Furthermore, human ALDH16A1 was significantly upregulated (4.79±1.00fold; p=0.00006) in CD34+ (enriched with HSC) as compared to CD34- (devoid of HSC) populations in umbilical cord blood.
Aldh16a1 is important for the maintenance of primitive hematopoiesis at early (18hpf) and angiogenesis at later (48,72 hpf) embryonic stages. As angiogenesis plays an important role in pathophysiology of malignancies, novel therapy against ALDH16A1 might be exploited in therapeutic intervention in cancer treatment. Moreover, a specific role of zebrafish aldh16a1 in primitive erythropoiesis and a higher level of ALDH16A1 expression in human HSC-enriched cells suggested a conserved mechanism whereby ALDH regulates hematopoiesis. / published_or_final_version / Medicine / Master / Master of Research in Medicine
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