Purpose: To quantify the number of SARS-CoV-2 infections in students and teachers in 14 Secondary schools in eastern Saxony, Germany. Seroprevalence of SARS-CoV-2 antibodies in study population. Number of undetected cases. - Methods: Serial seroprevalence study. - Results: The role of educational settings in the SARS-CoV-2 Pandemic is still controversial. Seroprevalence increases from 0.8 to 5.9% from October to December when schools remained open and to 12.2% in March/April during a strict lockdown with closed schools. The ratio of undetected to detected cases decreased from 0.76 to 0.44 during the study period. - Conclusion: During the second and third wave of the pandemic in Germany, students and teachers are not overrepresented in SARS-CoV-2 infections. The percentage of undetected cases is moderate and decreases over time. The risk of contracting SARS-CoV-2 within the household is higher than contracting it in educational settings making school closures rather ineffective in terms of pandemic control measures or individual risk reduction in children and adolescents. - Trial registration: DRKS00022455 (July 23rd, 2020).
| Identifer | oai:union.ndltd.org:DRESDEN/oai:qucosa:de:qucosa:91286 |
| Date | 06 June 2024 |
| Creators | Kirsten, Carolin, Kahre, Elisabeth, Blankenburg, Judith, Schumm, Leonie, Haag, Luise, Galow, Lukas, Unrath, Manja, Czyborra, Paula, Schneider, Josephine, Lück, Christian, Dalpke, Alexander H., Berner, Reinhard, Armann, Jakob |
| Publisher | Springer |
| Source Sets | Hochschulschriftenserver (HSSS) der SLUB Dresden |
| Language | English |
| Detected Language | English |
| Type | info:eu-repo/semantics/publishedVersion, doc-type:article, info:eu-repo/semantics/article, doc-type:Text |
| Rights | info:eu-repo/semantics/openAccess |
| Relation | 1439-0973, 10.1007/s15010-022-01824-9 |
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