The use of the herbicide glyphosate and its formulations on protein-rich feedstuff for cattle
leads to a considerable intake of glyphosate into the rumen of the animals, where
glyphosate may potentially impair the 5-enolpyruvylshikimate-3-phosphate pathway of
the commensal microbiota, which could cause dysbiosis or proliferation of pathogenic
microorganisms. Here, we evaluated the effects of pure glyphosate and the formulations
Durano TF and Roundup® LB plus in different concentrations on the fermentation pattern,
community composition and metabolic activity of the rumen microbiota using the Rumen
Simulation Technique (RUSITEC). Application of the compounds in three concentrations
(0.1mg/l, 1.0mg/l or 10mg/l, n=4 each) for 9days did not affect fermentation parameters
such as pH, redox potential, NH3-N concentration and production of short-chain fatty
acids compared to a control group. Microbial protein synthesis and the degradation of
different feed fractions did not vary among the treatments. None of the used compounds
or concentrations did affect the microbial diversity or abundance of microbial taxa.
Metaproteomics revealed that the present metabolic pathways including the shikimate
pathway were not affected by addition of glyphosate, Durano TF or Roundup® LB plus.
In conclusion, neither pure glyphosate, nor its formulations Durano TF and Roundup® LB
plus did affect the bacterial communities of the rumen.
| Identifer | oai:union.ndltd.org:DRESDEN/oai:qucosa:de:qucosa:85825 |
| Date | 06 June 2023 |
| Creators | Brede, Melanie, Haange, Sven-Bastiaan, Riede, Susanne, Engelmann, Beatrice, Jehmlich, Nico, Rolle-Kampzczyk, Ulrike, Rohn, Karl, von Soosten, Dirk, von Bergen, Martin, Breves, Gerhard |
| Publisher | Frontiers Media S.A. |
| Source Sets | Hochschulschriftenserver (HSSS) der SLUB Dresden |
| Language | English |
| Detected Language | English |
| Type | info:eu-repo/semantics/publishedVersion, doc-type:article, info:eu-repo/semantics/article, doc-type:Text |
| Rights | info:eu-repo/semantics/openAccess |
| Relation | 873101 |
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