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Comparative studies on the drug target proteins from two human malaria parasites

Purine nucleoside phosphorylase (PNP) and lactate dehydrogenase (LDH) from Plasmodium parasites are two potential targets for novel anti-malarial compounds. Whereas these enzymes have been well-characterised from the Plasmodium falciparum parasite, information on these enzymes from the similarly prevalent species, Plasmodium vivax, is very limited. This hinders the development of effective common anti-malarial compounds.

Identiferoai:union.ndltd.org:bl.uk/oai:ethos.bl.uk:503880
Date January 2009
CreatorsChaikuad, Apirat
PublisherUniversity of Bristol
Source SetsEthos UK
Detected LanguageEnglish
TypeElectronic Thesis or Dissertation

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