The title chroman is useful in synthesis and as a water-soluble analog of γ-tocopherol, a member of the vitamin E family. This new synthesis of γ-trolox proceeds via selective aromatic demethylation of Trolox, the more easily available 2,5,7,8-tetramethyl homolog compound. This route is shorter than the previous synthesis, avoids the use of cyanide and methoxybutadiene, and requires no chromatography.
Identifer | oai:union.ndltd.org:ETSU/oai:dc.etsu.edu:etsu-works-18742 |
Date | 01 January 2008 |
Creators | Hyatt, John |
Publisher | Digital Commons @ East Tennessee State University |
Source Sets | East Tennessee State University |
Detected Language | English |
Type | text |
Source | ETSU Faculty Works |
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