We have studied gas flow and particle deposition in a realistic three-dimensional model of the bronchial tree, extending from the trachea to the segmental bronchi (7th airway generation for the most distal ones) using Computational Fluid Dynamics (CFD). The model is based on the morphometrical data of Horsfield et al. [J. Appl. Physiol. 31: 207-217, 1971] and on bronchoscopic and CT images, which give the spatial 3D-orientation of the curved ducts. It incorporates realistic angles of successive branching planes. Steady inspiratory flow varying between 50cm³/s and 500cm³/s was simulated as well as deposition of spherical aerosol particles (1 to 7& / Doctorat en sciences appliquées / info:eu-repo/semantics/nonPublished
Identifer | oai:union.ndltd.org:ulb.ac.be/oai:dipot.ulb.ac.be:2013/211037 |
Date | 20 June 2005 |
Creators | Ertbruggen, Caroline van |
Contributors | Paiva, Manuel, Leduc, Bernard, Hendrick, Patrick, Degrez, Gérard, Hirsch, Charles, Riethmuller, Michel M.L. |
Publisher | Universite Libre de Bruxelles, Université libre de Bruxelles, Faculté de Médecine – Médecine, Bruxelles |
Source Sets | Université libre de Bruxelles |
Language | French |
Detected Language | English |
Type | info:eu-repo/semantics/doctoralThesis, info:ulb-repo/semantics/doctoralThesis, info:ulb-repo/semantics/openurl/vlink-dissertation |
Format | 1 v. (VII ,354 p.), No full-text files |
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