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Changes in the BCG-Induced T cell response over the first year of life

Includes bibliographical references (leaves 190-238). / Bacille Calmette-Guerin (BCG), the only currently available tuberculosis vaccine, is the most widely administered vaccine in the Expanded Programme on Immunisation (EPI). Despite this, many gaps in our knowledge of BCG-induced T cell responses exist. The primary objective of this study was to comprehensively delineate T cell immunity induced by BCG vaccination of newborns and to longitudinally assess BCG-specific T cell responses over the first year of life.

Identiferoai:union.ndltd.org:netd.ac.za/oai:union.ndltd.org:uct/oai:localhost:11427/14310
Date January 2011
CreatorsSoares, Andreia
ContributorsHanekom, Willem A
PublisherUniversity of Cape Town, Faculty of Health Sciences, Department of Paediatrics and Child Health
Source SetsSouth African National ETD Portal
LanguageEnglish
Detected LanguageEnglish
TypeDoctoral Thesis, Doctoral, PhD
Formatapplication/pdf

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