3D bioprinting is an emerging field with the potential to reform the process of organ transplantation. The ability to 3D print new organs and tissues would supplement the organ donor shortage and decrease the risk associated with organ rejection. One of the current areas of research focuses on printing cells using hydrogels composed of methacrylated compounds as a scaffolding. One of the chemical means of crosslinking the hydrogels is using the photoinitiator lithium phenyl-2,4,6-trimethylbenzoylphosphinate (LAP) to crosslink with light. The 3D bioprinter in the lab currently has an attachment for a 365nm lamp, however this is cytotoxic to cells. A 405nm laser was designed to mount on the hot tool of the BioAssemblyBot by Advanced Solutions and flash at a specific frequency when sent a signal from the bioprinter. This tool was then tested to determine effective flash frequencies for crosslinking hydrogels.
| Identifer | oai:union.ndltd.org:ucf.edu/oai:stars.library.ucf.edu:honorstheses-2569 |
| Date | 01 January 2023 |
| Creators | Morris, Lauren |
| Publisher | STARS |
| Source Sets | University of Central Florida |
| Language | English |
| Detected Language | English |
| Type | text |
| Format | application/pdf |
| Source | Honors Undergraduate Theses |
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