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Balloon‐assisted injection of fibrin sealant for the treatment of postintervention access‐site bleeding complications

This study sought to evaluate a new method that uses injection of fibrin sealant
under simultaneous balloon occlusion for the treatment of postinterventional access
site bleeding complications. With the rising complexity of interventional procedures,
iatrogenic false aneurysms and active bleeding has become more common. In general,
these complications are associated with increased morbidity and mortality,
especially if surgical repair is required. Although high success rates are reported for
ultrasound‐guided compression and ultrasound‐guided thrombin injection, these
methods are not always feasible. All procedures of fibrin sealant injection under
simultaneous balloon occlusion for the treatment of postinterventional access site
bleeding complications or pseudoaneurysm were prospectively collected. Additional
data were retrospectively obtained and analyzed for all patients treated by this new
method. In total, 53 patients were included from 2018 to 2021. Most of the access
site complications were related to transcatheter aortic valve replacement (40%) or
percutaneous coronary intervention (21%), but also to a wide variety of other procedures.
Of the 53 patients, 30 had to be treated for false aneurysms and 23 for
active bleeding. A high primary success rate of 94% was achieved. Recurrences of
false aneurysms occurred in six patients, of which only one needed open surgical
repair. Regarding complications, two peripheral embolisms, thereof one requiring
additional stent implantation occurred. Balloon‐assisted thrombin injection seems to
be feasible and safe. It provides a new alternative to prevent surgery for patients
where common techniques are unavailable or have failed.

Identiferoai:union.ndltd.org:DRESDEN/oai:qucosa:de:qucosa:86792
Date10 August 2023
CreatorsLindner, Jakob U., Markuske, Matthias, Szczanowicz, Lukasz, Jobs, Alexander, Abdel‐Wahab, Mohamed, Desch, Steffen, Thiele, Holger, Sulimov, Dmitry S.
PublisherWiley Interscience
Source SetsHochschulschriftenserver (HSSS) der SLUB Dresden
LanguageEnglish
Detected LanguageEnglish
Typeinfo:eu-repo/semantics/publishedVersion, doc-type:article, info:eu-repo/semantics/article, doc-type:Text
Rightsinfo:eu-repo/semantics/openAccess
Relation10.1002/ccd.30068

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