This study analyzed locomotor sensitization to methylphenidate (MPH, Trade name: Ritalin) in adolescent male and female rats. Females, but not males, demonstrated locomotor sensitization. Interestingly, females given MPH demonstrated a significant decrease of brain derived neurotrophic factor (BDNF) in the striatum, whereas males demonstrated an increase in this same brain area.
| Identifer | oai:union.ndltd.org:ETSU/oai:dc.etsu.edu:etsu-works-1951 |
| Date | 04 May 2012 |
| Creators | Roeding, Ross L., Perna, Marla K., Brown, Russell W. |
| Publisher | Digital Commons @ East Tennessee State University |
| Source Sets | East Tennessee State University |
| Detected Language | English |
| Type | text |
| Source | ETSU Faculty Works |
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