Characterization of impaired CD8+ T cell responses to Chlamydia trachomatis

Description

Chlamydia trachomatis infection is the most common bacterial sexually transmitted disease in the United States. Irregular screening to identify infected individuals and a lack of sterilizing immunity to C. trachomatis has led to a dramatic increase in the number of reported C. trachomatis infections over the last twenty years. Repeated infections with C. trachomatis lead to serious sequelae such as pelvic inflammatory disease and ectopic pregnancy, which can result in infertility.

Links & Downloads

1. Fankhauser, Sarah Carmela. 2013. Characterization of impaired CD8+ T cell responses to Chlamydia trachomatis. Doctoral dissertation, Harvard University.
2. http://dissertations.umi.com/gsas.harvard:11158
3. http://nrs.harvard.edu/urn-3:HUL.InstRepos:11169794

Tags

Immunology

Microbiology

CD8+ T cells

Chlamydia

Immunoinhibitory

PD-1

PD-L1

Additional Fields

Identifer	oai:union.ndltd.org:harvard.edu/oai:dash.harvard.edu:1/11169794
Date	15 October 2013
Creators	Fankhauser, Sarah Carmela
Contributors	Starnbach, Michael N.
Publisher	Harvard University
Source Sets	Harvard University
Language	en_US
Detected Language	English
Type	Thesis or Dissertation
Rights	open