The traditional picture of tissues, where they are treated as liquids defined by properties such
as surface tension or viscosity has been redefined during the last few decades by the more
fundamental question: under which conditions do tissues display liquid-like or solid-like
behaviour? As a result, basic concepts arising from the treatment of tissues as solid matter,
such as cellular jamming and glassy tissues, have shifted into the current focus of biophysical
research. Here, we review recent works examining the phase states of tissue with an emphasis
on jamming transitions in cancer. When metastasis occurs, cells gain the ability to leave the
primary tumour and infiltrate other parts of the body. Recent studies have shown that a linkage
between an unjamming transition and tumour progression indeed exists, which could be of
importance when designing surgery and treatment approaches for cancer patients
| Identifer | oai:union.ndltd.org:DRESDEN/oai:qucosa:de:qucosa:84934 |
| Date | 25 April 2023 |
| Creators | Oswald, Linda, Grosser, Steffen, Smith, David M., Käs, Josef A. |
| Publisher | IOP Publishing |
| Source Sets | Hochschulschriftenserver (HSSS) der SLUB Dresden |
| Language | English |
| Detected Language | English |
| Type | info:eu-repo/semantics/publishedVersion, doc-type:article, info:eu-repo/semantics/article, doc-type:Text |
| Rights | info:eu-repo/semantics/openAccess |
| Relation | 1361-6463, 483001 |
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