Variations in anxiety-related behavior are associated with individual allostatic set-points in
chronically stressed rats. Actively offensive rats with the externalizing indicators of sniffing
and climbing the stimulus and material tearing during 10 days of predator scent stress had
reduced plasma corticosterone, increased striatal glutamate metabolites, and increased adrenal
11-dehydrocorticosterone content compared to passively defensive rats with the internalizing
indicators of freezing and grooming, as well as to controls without any behavioral changes.
These findings suggest that rats that display active offensive activity in response to stress develop
anxiety associated with decreased allostatic set-points and increased resistance to stress.
| Identifer | oai:union.ndltd.org:DRESDEN/oai:qucosa:de:qucosa:89512 |
| Date | 05 February 2024 |
| Creators | Ullmann, Enrico, Chrousos, George, Perry, Seth W., Wong, Ma-Li, Licinio, Julio, Bornstein, Stefan R., Tseilikman, Olga, Komelkova, Maria, Lapshin, Maxim S., Vasilyeva, Maryia, Zavjalov, Evgenii, Shevelev, Oleg, Khotskin, Nikita, Koncevaya, Galina, Khotskina, Anna S., Moshkin, Mikhail, Cherkasova, Olga, Sarapultsev, Alexey, Ibragimov, Roman, Kritsky, Igor, Fegert, Jörg M., Tseilikman, Vadim, Yehuda, Rachel |
| Publisher | MDPI |
| Source Sets | Hochschulschriftenserver (HSSS) der SLUB Dresden |
| Language | English |
| Detected Language | English |
| Type | info:eu-repo/semantics/publishedVersion, doc-type:article, info:eu-repo/semantics/article, doc-type:Text |
| Rights | info:eu-repo/semantics/openAccess |
| Relation | 7440 |
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