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An?lise dos lip?dios s?ricos de pacientes obesos m?rbidos submetidos ao bypass g?strico

Submitted by Setor de Tratamento da Informa??o - BC/PUCRS (tede2@pucrs.br) on 2015-09-28T12:08:49Z
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Previous issue date: 2015-01-20 / Introduction: The aim of this study was to evaluate the correlation between improvement in dyslipidemia and changes in body fat percentage.
Material and Method: We conducted an observational, retrospective cohort study of patients subjected to gastric bypass. We selected patients who underwent bioimpedance analysis before surgery and at 3, 6 and 12 months postoperatively. Patients underwent laboratory tests and anthropometric measurements at the same time.
Results: We studied 228 patients with a mean age of 37.4 ? 11.7 years. Most patients were female (76.3%). Initially, 143 patients (66.2%) showed criteria for dyslipidemia, and 6 months after surgery, this number fell to 83 patients (50.6%) and continued falling over time to only 45 patients (28.5%) 12 months after surgery. In relating different variables with the decrease in percent body fat at 12 months, a significant association was seen with weight loss (r=0.258; p=0.009), BMI (r=0.272; p=0.005) and waist circumference (r=0.357, p <0.001). However, the only biochemical parameter showing a significant association was HDL-C level (r=-0.267; p=0.009). Patients with the greatest decrease in body fat percentage were those with the largest decrease in weight, BMI and waist circumference and highest increase in HDL-C level.
Conclusion: This study demonstrated the association of decrease in percent body fat with increase in HDL-C, regardless of sex and age. The same association was also observed when using the parameters BMI, weight loss and waist circumference. / Introdu??o: O objetivo deste estudo ? avaliar a correla??o entre a melhora da dislipidemia e as altera??es do percentual de gordura corporal.
Material e M?todo: Realizamos uma coorte observacional e retrospectiva, pacientes submetidos ao Bypass g?strico. Foram selecionados pacientes que realizaram bioimped?ncia antes da cirurgia e nos meses 3, 6 e 12 de p?s-operat?rio. Os pacientes realizaram exames laboratoriais e medidas antropom?tricas no mesmo momento.
Resultados: Foram avaliados 228 pacientes com m?dia de idade de 37,4?11,7 anos. A predomin?ncia foi do sexo feminino (76,3%). Inicialmente 143 pacientes (66,2%) apresentavam crit?rios para dislipidemia e ap?s 6 m?s de cirurgia este n?mero caiu para 83 pacientes (50,6%) e continuou reduzindo at? um ano p?s-cir?rgico chegando a apenas 45 pacientes (28,5%) ap?s 12 meses de cirurgia. Na avalia??o da associa??o das vari?veis com a redu??o do percentual de gordura corporal aos 12 meses, as que se associaram significativamente foram a redu??o do peso (r=0,258; p=0,009), IMC (r=0,272; p=0,005) e circunfer?ncia abdominal (r=0,357; p<0,001). No entanto, com os par?metros bioqu?micos a associa??o foi significativa apenas com os n?veis de HDL (r=-0,267; p=0,009). Pacientes com maior redu??o do percentual de gordura corporal foram os que mais reduziram o peso, IMC e circunfer?ncia abdominal e tamb?m foram os que mais aumentaram os n?veis de HDL.
Conclus?o: Este trabalho evidenciou a associa??o da redu??o do percentual de gordura corporal com o aumento do HDL, independente do sexo e da idade. A mesma associa??o tamb?m foi observada quando utilizados os par?metros IMC, redu??o de peso e medida da circunfer?ncia abdominal.

Identiferoai:union.ndltd.org:IBICT/oai:tede2.pucrs.br:tede/6329
Date20 January 2015
CreatorsLubianca, Luiza Marsiaj
ContributorsPadoin, Alexandre Vontobel
PublisherPontif?cia Universidade Cat?lica do Rio Grande do Sul, Programa de P?s-Gradua??o em Medicina e Ci?ncias da Sa?de, PUCRS, Brasil, Faculdade de Medicina
Source SetsIBICT Brazilian ETDs
LanguagePortuguese
Detected LanguageEnglish
Typeinfo:eu-repo/semantics/publishedVersion, info:eu-repo/semantics/masterThesis
Formatapplication/pdf
Sourcereponame:Biblioteca Digital de Teses e Dissertações da PUC_RS, instname:Pontifícia Universidade Católica do Rio Grande do Sul, instacron:PUC_RS
Rightsinfo:eu-repo/semantics/openAccess
Relation7620745074616285884, 600, 600, 600, -8624664729441623247, -969369452308786627

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