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Antimicrobial Roles for iNKT Cells and GM-CSF in Mycobacterium Tuberculosis Infection

Despite effective antibiotics, Mycobacterium tuberculosis (Mtb), the causative agent of tuberculosis, still infects nearly one-third of the world's population. While key immune factors including CD4+ T cells and IFNg production have been identified, there are still many antimicrobial mechanisms yet to be explored. Here we characterized the role of invariant natural killer T (iNKT) cells and GM-CSF during Mtb infection.

Identiferoai:union.ndltd.org:harvard.edu/oai:dash.harvard.edu:1/12271798
Date04 June 2016
CreatorsRothchild, Alissa Chen
ContributorsBehar, Samuel Maurice
PublisherHarvard University
Source SetsHarvard University
Languageen_US
Detected LanguageEnglish
TypeThesis or Dissertation
Rightsopen

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