Ip Lai Nang. / Thesis (M.Phil.)--Chinese University of Hong Kong, 2001. / Includes bibliographical references (leaves 67-71). / Abstracts in English and Chinese. / ABSTRACT (ENGLISH) --- p.iii / ABSTRACT (CHINESE) --- p.iv / ACKNOWLEDGEMENTS --- p.v / TABLE OF CONTENTS --- p.vi / LIST OF TABLES --- p.viii / LIST OF FIGURES --- p.ix / LIST OF APPENDIX --- p.x / Chapter CHAPTER 1 --- INTRODUCTION --- p.1 / Chapter CHAPTER 2 --- BACKGROUND --- p.3 / Chapter 2.1 --- Structure of DNA --- p.3 / Chapter 2.2 --- Sequence dependent stability --- p.8 / Chapter 2.3 --- Thermodynamics of DNA --- p.9 / Chapter 2.4 --- Model for predicting thermodynamic parameters of DNA sequence --- p.15 / Chapter 2.4.1 --- The nearest-neighbor (NN) model / Chapter 2.4.1.1 --- Background --- p.15 / Chapter 2.4.1.2 --- Method for predicting thermodynamic parameters --- p.16 / Chapter 2.4.1.3 --- Limitation of the NN model --- p.19 / Chapter CHAPTER 3 --- EXPERIMENTAL METHOD --- p.20 / Chapter 3.1 --- Design of DNA sequences PAGE --- p.20 / Chapter 3.2 --- DNA synthesis and purification --- p.22 / Chapter 3.3 --- UV measurement --- p.23 / Chapter CHAPTER 4 --- THE NEXT NEAREST-NEIGHBOR (NNN) MODEL --- p.27 / Chapter 4.1 --- Method for extracting the NNN thermodynamic parameters --- p.30 / Chapter 4.2 --- Discussions --- p.34 / Chapter 4.2.1 --- Comparison of the NN model and the NNN model --- p.34 / Chapter 4.2.2 --- The NNN effect --- p.38 / Chapter 4.2.3 --- Sequence-specific local structure of DNA and the NNN effect / Chapter CHAPTER 5 --- SUMMARY AND FUTURE WORK --- p.49 / APPENDIX I´ؤ XVI --- p.51 / REFERENCE --- p.67
| Identifer | oai:union.ndltd.org:cuhk.edu.hk/oai:cuhk-dr:cuhk_323550 |
| Date | January 2001 |
| Contributors | Ip, Lai Nang., Chinese University of Hong Kong Graduate School. Division of Chemistry. |
| Source Sets | The Chinese University of Hong Kong |
| Language | English, Chinese |
| Detected Language | English |
| Type | Text, bibliography |
| Format | print, xi, 71 leaves : ill. ; 30 cm. |
| Rights | Use of this resource is governed by the terms and conditions of the Creative Commons “Attribution-NonCommercial-NoDerivatives 4.0 International” License (http://creativecommons.org/licenses/by-nc-nd/4.0/) |
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