Pluripotent stem cell-based screening identifies CUDC-907 as an effective compound for restoring the in vitro phenotype of Nakajo-Nishimura syndrome / 多能性幹細胞を用いたスクリーニングによる、中條・西村症候群のin vitro表現型回復に有効な化合物としてのCUDC-907の特定

Description

京都大学 / 新制・課程博士 / 博士(医科学) / 甲第24532号 / 医科博第146号 / 新制||医科||10(附属図書館) / 京都大学大学院医学研究科医科学専攻 / (主査)教授 金子 新, 教授 上杉 志成, 教授 寺田 智祐 / 学位規則第4条第1項該当 / Doctor of Medical Science / Kyoto University / DFAM

Links & Downloads

1. http://hdl.handle.net/2433/283651
2. 10.14989/doctor.k24532
3. 14301

Tags

chemokines

hereditary autoinflammatory diseases

high-throughput screening assays

histone deacetylase inhibitors

LMP7 protein

pluripotent stem cells

491

Additional Fields

Identifer	oai:union.ndltd.org:kyoto-u.ac.jp/oai:repository.kulib.kyoto-u.ac.jp:2433/283651
Date	23 March 2023
Creators	Kase, Naoya
Contributors	加瀨, 直也, カセ, ナオヤ
Publisher	Kyoto University, 京都大学
Source Sets	Kyoto University
Language	English
Detected Language	English
Type	doctoral thesis, Thesis or Dissertation
Rights	Kase N, Terashima M, Ohta A et al. (2021) ""Pluripotent stem cell-based screening identifies CUDC-907 as an effective compound for restoring the in vitro phenotype of Nakajo-Nishimura syndrome"" STEM CELLS Translational Medicine (John Wiley & Sons, Ltd) 10(3), 455-464. DOI: 10.1002/sctm.20-0198 https://stemcellsjournals.onlinelibrary.wiley.com/doi/10.1002/sctm.20-0198
Relation	https://doi.org/10.1002/sctm.20-0198