Objective: Diet lifestyle can influence the risk of endometriosis. Therefore, we conducted
a systematicmeta-analysis to investigate the association between dairy products and the
risk of endometriosis. Besides, we performed a dose-responsemeta-analysis to evaluate
the amount of dairy intake affecting the risk of endometriosis.
Methods: Relevant studies were searched from Pubmed, Embase databases,
Cochrane Library, and Web of Science from the inception to November 6th, 2020. Also,
the dose-response meta-analysis was conducted. All the pooled results were performed
by risk ratios (RRs).
Results: Finally, seven high-quality studies were included in the present meta-analysis.
Total dairy intake was inversely associated with the risk of endometriosis, and the
risk of endometriosis tended to decrease with a decrease in the risk of endometriosis
when dairy products intake was over 21 servings/week (RR 0.87, 95% CI 0.76–1.00;
pnon−linearity = 0.04). Similarly, people who consumed more than 18 servings of high-fat
dairy products per week had a reduced risk of endometriosis (RR 0.86, 95% CI
0.76–0.96). When stratified-analyses were conducted based on specific dairy product
categories, it indicated that people with high cheese intake might have a reduced risk of
endometriosis (RR 0.86, 95%CI 0.74–1.00). Other specific dairy products such as whole
milk (RR 0.90, 95% CI 0.72–1.12), reduced-fat/skim milk (RR 0.83, 95% CI 0.50–1.73),
ice cream (RR 0.83, 95% CI 0.50–1.73), and yogurt (RR 0.83, 95% CI 0.62–1.11) have
not shown significant evidence of an association with the risk of endometriosis. However,
there is a higher risk of endometriosis in the females with high butter intake compared to
females with low butter intake (1.27, 95% CI 1.03–1.55).
Conclusions: Overall, dairy products intake was associated with a reduction in
endometriosis, with significant effects when the average daily intake 3 servings. When
analyzed according to the specific type of dairy product, it was shown that females with
higher high-fat dairy and cheese intake might have a reduced risk of endometriosis.
However, high butter intake might be associated to the increased risk of endometriosis.
More future studies are needed to validate and add to this finding.
| Identifer | oai:union.ndltd.org:DRESDEN/oai:qucosa:de:qucosa:84353 |
| Date | 28 March 2023 |
| Creators | Qi, Xiangying, Zhang, Wenyan, Ge, Mingxiu, Sun, Qiang, Peng, Lei, Cheng, Wenke, Li, Xuepeng |
| Publisher | Frontiers Research Foundation |
| Source Sets | Hochschulschriftenserver (HSSS) der SLUB Dresden |
| Language | English |
| Detected Language | English |
| Type | info:eu-repo/semantics/publishedVersion, doc-type:article, info:eu-repo/semantics/article, doc-type:Text |
| Rights | info:eu-repo/semantics/openAccess |
| Relation | 2296-861X, 701860 |
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