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Previous issue date: 2016-03-29 / Funda??o de Amparo ? Pesquisa do Estado da Bahia - FAPEB / Periodontitis is a multifactorial disease, bacterial primary etiology, but presents external factors that influence its development. It has also been considered exposure to systemic diseases, such as the circulatory system. Objective: To investigate the role of psychological factors in periodontitis, considering it as the outcome as well as the influence of the level of periodontitis severity, as the exposure factor on acute myocardial infarction. Methods: This investigation is a result of data from a previous case-control study that estimated the association between periodontitis and acute myocardial infarction and it was divided into two stages. At first, it was conducted two cross-sectional studies to assess the association between common mental disorders and periodontitis (study 1) and between stress and periodontitis (study 2) in 621 individuals. The application of a questionnaire was carried out to obtain socioeconomic, demographic, lifestyle and health-related information. The common mental disorder was assessed by the Self Reporting Questionnaire (SRQ-20) and stress, the Perceived Stress Scale. The diagnosis of periodontitis was conducted from complete periodontal examination using: clinical attachment level, probing depth and bleeding on probing. Prevalence ratios (PR) and confidence intervals at 95% (95%CI) were obtained by Poisson regression analysis. In the second stage, a case-control study estimated the effect of the levels of periodontitis severity on acute myocardial infarction (study 3), with 207 individuals in the case group treated in the emergency Hospitals Santa Izabel and Ana Nery in Salvador, Bahia, Brazil, diagnosed with first acute myocardial infarction event, and 407 in the control group, without a diagnosis of acute myocardial infarction. Two criteria were used to define the levels of periodontitis severity. Unconditional logistic regression analysis was used to investigate the association between the levels of periodontitis severity and acute myocardial infarction: odds ratio (OR) and 95%CI.Results: The findings were presented in articles. Article 1 - showed that the occurrence of periodontitis among those exposed to common mental disorders was approximately 50% higher than in those without this mental condition, even after adjustment for age, sex, family income, current smoking habit, alcohol beverage consumption and cardiovascular disease (RPadjusted = 1.54, 95% CI: [1.13 to 2.10]). Article 2 - the measurements have demonstrated a positive association between stress and periodontitis, regardless the definition of the outcome: probing depth ? 4 mm (RPadjusted = 1.28, 95%CI: [1.04 to 1.58]), clinical attachment level ? 5mm (RPadjusted= 1.15, 95%CI: [1.01 to 1.31]) and periodontitis (RPadjusted= 1.36, 95%CI: [1.01 to 1.83]), after adjustment for age, sex, schooling level, current smoking habit, pulmonary disease and body mass index.Article 3 - strong positive association was found between severe and moderate periodontitis (RPadjusted = 2.21 to 3.92, and 1.96 to 2.51, respectively) with acute myocardial infarction, with statistical significance (p ? 0.05) for both diagnostic criteria of periodontitis. Conclusions: positive association between psychological factors and periodontitis has been demonstrated, as well as the dose-response effect of levels of periodontitis severity on acute myocardial infarction. / A periodontite ? uma enfermidade multifatorial,de etiologia prim?ria bacteriana, por?m apresenta fatores externos que influenciam no seu desenvolvimento. Tamb?m tem sido considerada exposi??o para doen?as sist?micas, a exemplo do aparelho circulat?rio. Objetivo: Investigar o papel dos fatores psicol?gicos na periodontite, considerando-a como desfecho, bem como a influ?ncia do n?vel de gravidade da periodontite, como fator de exposi??o, sobre o infarto agudo do mioc?rdio. M?todo: Esta investiga??o? decorrente de dados de um estudo caso-controle pr?vio que estimou a associa??o entre a presen?a de periodontitee o infarto agudo do mioc?rdio e foi dividida em duas etapas. Na primeira, foram conduzidos dois estudos de corte transversal, para avaliar a associa??o entre o transtorno mental comume a periodontite (estudo 1) e entre o estresse e a periodontite(estudo 2) em 621 indiv?duos. A aplica??o de um question?rio foi realizada para obten??o de informa??es socioecon?mico-demogr?ficas, h?bitos de vida e relativas ? sa?de. O transtorno mental comum foi avaliado a partir do Self Reporting Questionnaire (SRQ-20) e o estresse, pela Escala de Estresse Percebido. O diagn?stico de periodontite foi realizado a partir de exame periodontal completo, empregando: n?vel de inser??o cl?nica, profundidade de sondagem e sangramento ? sondagem. As raz?es de preval?ncia (RP) e respectivos intervalos de confian?a a 95% (IC95%) foram obtidas pela an?lise de regress?o de Poisson. Na segunda etapa, um estudo caso-controle estimou o efeito de n?veis de gravidade da periodontite no infarto agudo do mioc?rdio (estudo 3), com 207 indiv?duos do grupo caso, atendidos na emerg?ncia dos Hospitais Santa Izabel e Ana Nery em Salvador, Bahia, Brasil, diagnosticados com o primeiro evento de infarto agudo do mioc?rdio,e 407 do grupo controle, sem diagn?stico de infarto agudo do mioc?rdio.Dois crit?rios foram empregados para definir os n?veis de gravidade da periodontite. An?lise de regress?o log?stica n?o condicional foi usada para investigar a associa??o entre os n?veis de gravidade da periodontite e o infarto agudo do mioc?rdio: odds ratio (OR) e IC95%. Resultados: Os achados foram apresentados em forma de artigo. Artigo 1 -mostraram que a ocorr?ncia de periodontite entre aqueles expostos ao transtorno mental comum foi, aproximadamente, 50% maior que naqueles sem esta condi??o mental, mesmo ap?s ajuste por: idade, sexo, renda familiar, h?bito de fumar atual, consumo de bebida alco?lica e doen?a cardiovascular (RPajustada = 1,54, IC95%: [1,13 ? 2,10]). Artigo 2 -as medidas demonstraram existir associa??o positiva entre estresse e periodontite, independentemente da defini??o do desfecho: profundidade de sondagem ? 4mm (RPajustada= 1,28, IC95%: [1,04-1,58]), n?vel de inser??o cl?nica ? 5mm (RPajustada= 1,15, IC95%: [1,01-1,31]) e periodontite (RPajustada= 1,36, IC95%: [1,01-1,83]), ap?s ajuste para idade, sexo, n?vel de escolaridade, h?bito de fumar atual, doen?a pulmonar e ?ndice de massa corporal.Artigo 3 -associa??o positiva forte foi verificada entre as periodontites grave e moderada (RPajustada= 2,21 a 3,92; e 1,96 a 2,51, respectivamente) com o infarto agudo do mioc?rdio, com signific?ncia estat?stica (p? 0,05), para ambos os crit?rios de diagn?stico da periodontite. Conclus?es: associa??o positiva entre os fatores psicol?gicos e presen?a de periodontite foi demonstrada, assim como o efeito dose-resposta dos n?veis de gravidade da periodontite sobre o infarto agudo do mioc?rdio.
| Identifer | oai:union.ndltd.org:IBICT/oai:tede2.uefs.br:8080:tede/464 |
| Date | 29 March 2016 |
| Creators | Miranda, Samilly Silva |
| Contributors | Gomes Filho, Isaac Suzart |
| Publisher | Universidade Estadual de Feira de Santana, Mestrado Acad?mico em Sa?de Coletiva, UEFS, Brasil, DEPARTAMENTO DE SA?DE |
| Source Sets | IBICT Brazilian ETDs |
| Language | Portuguese |
| Detected Language | English |
| Type | info:eu-repo/semantics/publishedVersion, info:eu-repo/semantics/masterThesis |
| Format | application/pdf |
| Source | reponame:Biblioteca Digital de Teses e Dissertações da UEFS, instname:Universidade Estadual de Feira de Santana, instacron:UEFS |
| Rights | info:eu-repo/semantics/openAccess |
| Relation | -2122225376607208326, 600, 600, 600, 600, 600, 1006395569471477890, -6173167103754495199, -1614662311676629386, -8233071094704392586 |
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