Return to search

Biocatalytically Triggered Co‐Assembly of Two‐Component Core/Shell Nanofibers

Yes / For the development of applications and novel uses for peptide nanostructures, robust routes for their surface functionalization, that ideally do not interfere with their self‐assembly properties, are required. Many existing methods rely on covalent functionalization, where building blocks are appended with functional groups, either pre‐ or post‐assembly. A facile supramolecular approach is demonstrated for the formation of functionalized nanofibers by combining the advantages of biocatalytic self‐assembly and surfactant/gelator co‐assembly. This is achieved by enzymatically triggered reconfiguration of free flowing micellar aggregates of pre‐gelators and functional surfactants to form nanofibers that incorporate and display the surfactants’ functionality at the surface. Furthermore, by varying enzyme concentration, the gel stiffness and supramolecular organization of building blocks can be varied. / FP7 Marie Curie Actions of the European Commission. Grant Number: 289723; EPSRC; HFSP; ERC; Leverhulme Trust

Identiferoai:union.ndltd.org:BRADFORD/oai:bradscholars.brad.ac.uk:10454/17082
Date09 November 2013
CreatorsAbul-Haija, Y.M., Roy, S., Frederix, P.W.J.M., Javid, Nadeem, Jayawarna, V., Ulijn, R.V.
Source SetsBradford Scholars
LanguageEnglish
Detected LanguageEnglish
TypeArticle, Accepted manuscript
Rights© 2014 Wiley. This is the peer-reviewed version of the following article: Abul-Haija YM, Roy S, Frederix PWJM et al (2014) Biocatalytically Triggered Co‐Assembly of Two‐Component Core/Shell Nanofibers. Small. 10(5): 973-979., which has been published in final form at https://doi.org/10.1002/smll.201301668. This article may be used for non-commercial purposes in accordance with Wiley Terms and Conditions for Self-Archiving., Unspecified

Page generated in 0.0022 seconds