Using a rat model, the effects of a single dose or six to twelve months of daily oral administration of ethanol on the immune system were determined. The rats were challenged with sheep red blood cells after the various dosing periods to elicit an immune response. Immune system responsiveness was determined by means of white blood cell counts and differentials, antibody titers, and T-cell numbers. No deleterious effects of the ethanol on the immune response were seen, while the female alcohol-fed rats showed a significant increase in T-Cell numbers, white blood cell counts, and lymphocytes over the sham group.
| Identifer | oai:union.ndltd.org:unt.edu/info:ark/67531/metadc501247 |
| Date | 08 1900 |
| Creators | Follin, Cynthia A. (Cynthia Ann) |
| Contributors | Lott, James R., Goven, Arthur James, 1950-, Fuchs, Jannon Lou, 1946- |
| Publisher | University of North Texas |
| Source Sets | University of North Texas |
| Language | English |
| Detected Language | English |
| Type | Thesis or Dissertation |
| Format | v, 44 leaves, Text |
| Rights | Public, Copyright, Follin, Cynthia A. (Cynthia Ann), Copyright is held by the author, unless otherwise noted. All rights reserved. |
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