We aimed to evaluate possible factors influencing the long-term survival of teeth after
tumor therapy to the head and neck region with and without radiation. Between January 2019
and January 2020, patients who underwent for head and neck cancer and received dental treatment
before and after at the Department of Prosthetic Dentistry of the Martin Luther University Halle-
Wittenberg were enrolled in the study. Clinical examination with assessment of dental status and
stimulated salivary flow rate (SFR) was performed and information about disease progression and
therapy was retrieved from medical records. Of 118 patients (male: 70.3%; mean age: 63.2 12.4
years), 95 received radiotherapy (RT), and 47 were administered radio-chemotherapy (RCT). The
teeth of irradiated patients exhibited a lower 5-year survival probability (74.2%) than those of nonirradiated
patients (89.4%). The risk of loss (RL) after RT increased with nicotine use, presence of
intraoral defects, reduced SFR, RCT and regarding mandibular teeth, and decreased with crowning
following. Lower SFR increased the RL even without RT. Consideration of patient’s treatment
history, individual risk profile, and clinical findings during the prosthetic planning phase could enable earlier, more targeted dental treatment after (e.g., timely crowning).
| Identifer | oai:union.ndltd.org:DRESDEN/oai:qucosa:de:qucosa:92136 |
| Date | 19 June 2024 |
| Creators | Schweyen, Ramona, Reich, Waldemar, Vordermark, Dirk, Kuhnt, Thomas, Wienke, Andreas, Hey, Jeremias |
| Publisher | MDPI |
| Source Sets | Hochschulschriftenserver (HSSS) der SLUB Dresden |
| Language | English |
| Detected Language | English |
| Type | info:eu-repo/semantics/publishedVersion, doc-type:article, info:eu-repo/semantics/article, doc-type:Text |
| Rights | info:eu-repo/semantics/openAccess |
| Relation | 2077-0383, 10.3390/jcm11206222 |
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