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Pertin?ncia da citologia anal em mulheres com les?o genital HPV-induzida

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Previous issue date: 2016-04-19 / O trabalho foi realizado como requisito para a obten??o do t?tulo de Mestre em Ci?ncias da Sa?de no Programa de P?s-Gradua??o em Ci?ncias da Sa?de da Universidade Federal do Rio Grande do Norte. O programa constitui uma proposta multidisciplinar onde temos a oportunidade de trocar ideias e conhecer experi?ncias de diversos profissionais da ?rea, e inclui disciplinas que ampliam o nosso campo de vis?o. Os conhecimentos de estat?stica, reda??o de trabalho cient?fico e pr?ticas educativas foram fundamentais para n?o restringir o nosso olhar a ser simplesmente m?dico. Foram produzidos tr?s artigos a partir da pesquisa realizada. O primeiro trata-se de uma revis?o bibliogr?fica por meio dos portais Pubmed, Embase, Scielo, Web of science e Cancerlit utilizando as palavras-chaves HPV, citologia, anal e c?ncer. Os demais artigos resultaram dos dados colhidos de um estudo transversal em 200 mulheres com e sem les?o genital que foram recrutados para exames de Papanicolaou anais. As mulheres que tiveram resultados anormais a partir de Atipia de C?lulas Escamosas foram classificadas como citologia anal anormal. A m?dia de idade foi de 41 anos. A maioria ? de pele n?o branca (56%), com at? 08 anos de escolaridade (50,5%) e n?o fumantes (91,5%). Quanto ? descri??o de vari?veis contextuais, 63,5% utilizava m?todos anticoncepcionais, 80% j? tinham ficado gr?vidas e destas, 30% tiveram algum tipo de aborto, a maioria possu?a at? tr?s parceiros (73,5%) e n?o referia nenhuma DST anterior (74%). Mais da metade relatou que n?o praticava sexo anal (75,5%), 91% referia que seus parceiros n?o tinham HPV, n?o usavam drogas (87,5%) e n?o mantinham rela??es bissexuais (96,5%). A maior parte das mulheres n?o possu?a nenhuma alergia (85%), patologia anal (92%) ou sangramento anal (68,5%), por?m mais da metade possu?a LIEG (les?o intraepitelial escamosa genital) (57,5%) e uma expressiva quantidade apresentava citologia anal anormal (13%). Observou-se uma associa??o significativa entre a citologia anal anormal e as mulheres que apresentavam LIEG (RP=2,46; p=0,032) demonstrando ser importante a pesquisa de citologia anal nesse grupo de pacientes. / The study was conducted as a requirement for obtaining the title of Master in the Health Sciences Program of the Federal University of Rio Grande do Norte. The program has a multidisciplinary proposal where we have the opportunity to exchange ideas and to know multi-professional experience, including subjects that expand our field of vision. The knowledge of topics such as analytical, scientific paper writing and educational practices were essential not to restrict our attention as a doctor. The survey produced three articles: the first one is a literature review through Pubmed portals, Embase, Scielo, Web of Science and CancerLit using keywords HPV, cytology, and anal cancer. The other articles resulted from data collected from a cross-sectional study in 200 women with and without genital lesions who were recruited for anal Pap smears. Women who had abnormal results from Atypical Squamous Cells were classified as abnormal anal cytology. The average age was 41 years. Most are non-white skin (56%), with up to eight years of education (50.5%) and non-smokers (91.5%). Regarding the description of contextual variables, 63.5% used contraceptive methods, 80% had been pregnant and of these, 30% had some abortion, most had up to three partners (73.5%) and did not report any previous STD (74%). More than half indicated that did not practice anal sex (75.5%), 91% stated that their partners did not have HPV, did not use drugs (87.5%) and not had bisexual relations (96.5%). Most women did not have any allergies (85%), anal pathology (92%) or anal bleeding (68.5%), but more than half had GSIL (genital squamous intraepithelial lesion) (57.5%) and a significant amount had abnormal anal cytology (13%). There was a significant association between abnormal anal cytology and GSIL (PR = 2.46; p = 0.032) demonstrating that is important to perform anal cytology in this group of patients.

Identiferoai:union.ndltd.org:IBICT/oai:repositorio.ufrn.br:123456789/21469
Date19 April 2016
CreatorsSilva, Maria do Perp?tuo Socorro Nobre Medeiros e
Contributors42252725400, Ara?jo, Ivonete Batista de, 05614082468, Carvalho, Maria Goretti Freire de, 05601592420, Oliveira, Ana Katherine da Silveira Gon?alves de
PublisherPROGRAMA DE P?S-GRADUA??O EM CI?NCIAS DA SA?DE, UFRN, Brasil
Source SetsIBICT Brazilian ETDs
LanguagePortuguese
Detected LanguageEnglish
Typeinfo:eu-repo/semantics/publishedVersion, info:eu-repo/semantics/masterThesis
Sourcereponame:Repositório Institucional da UFRN, instname:Universidade Federal do Rio Grande do Norte, instacron:UFRN
Rightsinfo:eu-repo/semantics/openAccess

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