Fluctuating ovarian hormones have been shown to affect decision-making processes in
women. While emerging evidence suggests effects of endogenous ovarian hormones
such as estradiol and progesterone on value-based decision-making in women, the
impact of exogenous synthetic hormones, as in most oral contraceptives, is not clear. In a
between-subjects design, we assessed measures of value-based decision-making in
three groups of women aged 18 to 29 years, during (1) active oral contraceptive intake
(N = 22), (2) the early follicular phase of the natural menstrual cycle (N = 20), and (3) the
periovulatory phase of the natural menstrual cycle (N = 20). Estradiol, progesterone,
testosterone, and sex-hormone binding globulin levels were assessed in all groups via
blood samples. We used a test battery which measured different facets of value-based
decision-making: delay discounting, risk-aversion, risk-seeking, and loss aversion. While
hormonal levels did show the expected patterns for the three groups, there were no
differences in value-based decision-making parameters. Consequently, Bayes factors
showed conclusive evidence in support of the null hypothesis. We conclude that women
on oral contraceptives show no differences in value-based decision-making compared to
the early follicular and periovulatory natural menstrual cycle phases.
| Identifer | oai:union.ndltd.org:DRESDEN/oai:qucosa:de:qucosa:85838 |
| Date | 07 June 2023 |
| Creators | Lewis, Carolin A., Kimmig, Ann-Christin S., Kroemer, Nils B., Pooseh, Shakoor, Smolka, Michael N., Sacher, Julia, Derntl, Birgit |
| Publisher | Frontiers Media S.A. |
| Source Sets | Hochschulschriftenserver (HSSS) der SLUB Dresden |
| Language | English |
| Detected Language | English |
| Type | info:eu-repo/semantics/publishedVersion, doc-type:article, info:eu-repo/semantics/article, doc-type:Text |
| Rights | info:eu-repo/semantics/openAccess |
| Relation | 817825 |
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