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Human Breast Milk: From Food to Active Immune Response With Disease Protection in Infants and Mothers

Breastfeeding is associated with long-term wellbeing including low risks of infectious
diseases and non-communicable diseases such as asthma, cancer, autoimmune
diseases and obesity during childhood. In recent years, important advances have been
made in understanding the human breast milk (HBM) composition. Breast milk
components such as, non-immune and immune cells and bioactive molecules, namely,
cytokines/chemokines, lipids, hormones, and enzymes reportedly play many roles in
breastfed newborns and in mothers, by diseases protection and shaping the immune
system of the newborn. Bioactive components in HBM are also involved in tolerance and
appropriate inflammatory response of breastfed infants if necessary. This review
summarizes the current literature on the relationship between mother and her infant
through breast milk with regard to disease protection. We will shed some light on the
mechanisms underlying the roles of breast milk components in the maintenance of health
of both child and mother.

Identiferoai:union.ndltd.org:DRESDEN/oai:qucosa:de:qucosa:85859
Date08 June 2023
CreatorsLokossou, Gatien A.G., Kouakanou, LĂ©once, Schumacher, Anne, Zenclussen, Ana C.
PublisherFrontiers Media S.A.
Source SetsHochschulschriftenserver (HSSS) der SLUB Dresden
LanguageEnglish
Detected LanguageEnglish
Typeinfo:eu-repo/semantics/publishedVersion, doc-type:article, info:eu-repo/semantics/article, doc-type:Text
Rightsinfo:eu-repo/semantics/openAccess
Relation849012

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