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Construction of DNA–polymer hybrids using intercalation interactions

No / Reversible addition–fragmentation chain transfer (RAFT) polymerisation was used to produce a range of polymers terminated with an acridine group, which intercalates efficiently into dsDNA; the structure of the polymer determines the nature and strength of the interaction. Using a short 63 base pair dsDNA, discrete and well-defined DNA–polymer hybrid nanoparticles were formed, which were characterised by dynamic light scattering, small-angle X-ray scattering and atomic force microscopy. / University of Warwick, EPSRC, Swiss National Science Foundation

Identiferoai:union.ndltd.org:BRADFORD/oai:bradscholars.brad.ac.uk:10454/15342
Date17 December 2013
CreatorsWilks, T.R., Pitto-Barry, Anaïs, Kirby, N., Stulz, E., O'Reilly, R.K.
Source SetsBradford Scholars
LanguageEnglish
Detected LanguageEnglish
TypeArticle, No full-text in the repository

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