The laminin-binding integrin (LBI) family are cell adhesion molecules that are essential for invasion and metastasis of human epithelial cancers and cell adhesion mediated drug resistance. We investigated whether copy number alteration (CNA) or mutations of a five-gene signature (ITGB4, ITGA3, LAMB3, PLEC, and SYNE3), representing essential genes for LBI adhesion, would correlate with patient outcomes within human epithelial-type tumor data sets currently available in an open access format.
| Identifer | oai:union.ndltd.org:arizona.edu/oai:arizona.openrepository.com:10150/615112 |
| Date | January 2016 |
| Creators | Harryman, William L, Pond, Erika, Singh, Parminder, Little, Andrew S, Eschbacher, Jennifer M, Nagle, Raymond B, Cress, Anne E |
| Contributors | Univ Arizona, Ctr Canc |
| Publisher | E-CENTURY PUBLISHING CORP |
| Source Sets | University of Arizona |
| Language | English |
| Detected Language | English |
| Type | Article |
| Rights | Creative Commons Attribution Non-Commercial License |
| Relation | http://www.ajtr.org/files/ajtr0019463.pdf |
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