Lui, Wai Ting. / Thesis (M.Phil.)--Chinese University of Hong Kong, 2008. / Includes bibliographical references (leaves 96-106). / Abstracts in English and Chinese. / Abstract --- p.i / Acknowledgements --- p.v / Table of Content --- p.vii / List of Tables --- p.x / List of Figures --- p.xi / Publications --- p.xiii / Chapter Chapter 1 --- Innate Immunity --- p.1 / Chapter 1.1 --- Immunity --- p.1 / Chapter 1.1.1 --- Surface Barriers --- p.2 / Chapter 1.1.2 --- Cell-mediated Innate Immunity --- p.2 / Chapter 1.1.3 --- Humoral Innate Immunity --- p.3 / Chapter 1.2 --- Complement System --- p.4 / Chapter 1.2.1 --- The Classical Pathway --- p.5 / Chapter 1.2.2 --- The Alternative Pathway --- p.6 / Chapter 1.2.3 --- The lectin pathway --- p.7 / Chapter 1.3 --- Lectins --- p.8 / Chapter 1.3.1 --- Mannose binding lectin --- p.11 / Chapter 1.3.2 --- Ficolin --- p.11 / Chapter 1.3.2.1 --- L-ficolin --- p.12 / Chapter 1.3.2.2 --- H-ficolin --- p.12 / Chapter 1.3.2.3 --- M-ficolin --- p.13 / Chapter Chapter 2 --- Innate Immunity in Pregnancy --- p.15 / Chapter 2.1 --- Immune challenge --- p.15 / Chapter 2.2 --- Natural Antimicrobials --- p.15 / Chapter 2.3 --- Cell-mediated Immunity --- p.16 / Chapter 2.4 --- Humoral Immunity --- p.18 / Chapter Chapter 3 --- Current Study --- p.20 / Chapter 3.1 --- Aim and Objectives --- p.20 / Chapter 3.2 --- General Methodology --- p.21 / Chapter Chapter 4 --- Pattern recognition lectins in maternal liver and lung --- p.23 / Chapter 4.1 --- Introduction --- p.23 / Chapter 4.2 --- Materials and Methods --- p.23 / Chapter 4.2.1 --- Animals --- p.23 / Chapter 4.2.2 --- Protein extraction --- p.27 / Chapter 4.2.3 --- Antibodies --- p.27 / Chapter 4.2.4 --- Western Blot --- p.28 / Chapter 4.2.5 --- Immunohistochemistry --- p.29 / Chapter 4.3 --- Results --- p.31 / Chapter 4.3.1 --- Temporal expression of lectins in maternal liver in mice --- p.31 / Chapter 4.3.2 --- Temporal expression of lectins in maternal lung in mice --- p.31 / Chapter 4.3.3 --- Spatial expression of lectins in maternal liver in mice --- p.34 / Chapter 4.3.4 --- Spatial expression of lectins in maternal lung in mice --- p.37 / Chapter 4.4 --- Discussion --- p.39 / Chapter 4.5 --- Conclusion --- p.40 / Chapter Chapter 5 --- Pattern recognition lectins in endometrium --- p.42 / Chapter 5.1 --- Introduction --- p.42 / Chapter 5.2 --- Materials and Methods --- p.43 / Chapter 5.2.1 --- Animals --- p.43 / Chapter 5.2.2 --- Immunohistochemistry --- p.45 / Chapter 5.3 --- Results --- p.45 / Chapter 5.4 --- Discussion --- p.48 / Chapter 5.5 --- Conclusion --- p.50 / Chapter Chapter 6 --- Pattern recognition lectins in maternal-fetal interface --- p.51 / Chapter 6.1 --- Introduction --- p.51 / Chapter 6.2 --- Materials and Methods --- p.52 / Chapter 6.2.1 --- Animals --- p.52 / Chapter 6.2.2 --- Immunohistochemistry --- p.55 / Chapter 6.3 --- Results --- p.55 / Chapter 6.4 --- Discussion --- p.58 / Chapter 6.5 --- Conclusion --- p.59 / Chapter Chapter 7 --- Pattern recognition lectins in preeclampsia --- p.60 / Chapter 7.1 --- Introduction --- p.60 / Chapter 7.2 --- Materials and Methods --- p.62 / Chapter 7.2.1 --- Patients --- p.62 / Chapter 7.2.2 --- Protein extraction --- p.63 / Chapter 7.2.3 --- Western Blot --- p.63 / Chapter 7.2.4 --- Lectin immunohistochemistry --- p.64 / Chapter 7.2.5 --- Apoptosis immunohistochemistry --- p.65 / Chapter 7.3 --- Results --- p.66 / Chapter 7.3.1 --- Expression levels of ficolins in normal and preeclamptic placenta --- p.67 / Chapter 7.3.2 --- Spatial expression of ficolins in normal and preeclamptic placenta --- p.68 / Chapter 7.3.3 --- Co-localization of Fas and ficolins in preeclamptic placenta --- p.69 / Chapter 7.4 --- Discussion --- p.71 / Chapter 7.5 --- Conclusion --- p.75 / Chapter Chapter 8 --- Pattern recognition lectins in miscarriage --- p.76 / Chapter 8.1 --- Introduction --- p.76 / Chapter 8.2 --- Materials and Methods --- p.77 / Chapter 8.2.1 --- Patients --- p.77 / Chapter 8.2.2 --- Immunohistochemistry --- p.78 / Chapter 8.3 --- Results --- p.79 / Chapter 8.3.1 --- Spatial expression of lectins in normal placenta and placenta from miscarriage patients --- p.80 / Chapter 8.3.2 --- Spatial expression of lectins in normal decidua and decidua from miscarriage patients --- p.86 / Chapter 8.4 --- Discussion --- p.92 / Chapter 8.5 --- Conclusion --- p.93 / Chapter Chapter 9 --- Future plan --- p.94 / References --- p.96
| Identifer | oai:union.ndltd.org:cuhk.edu.hk/oai:cuhk-dr:cuhk_326456 |
| Date | January 2008 |
| Contributors | Lui, Wai Ting., Chinese University of Hong Kong Graduate School. Division of Obstetrics and Gynaecology. |
| Source Sets | The Chinese University of Hong Kong |
| Language | English, Chinese |
| Detected Language | English |
| Type | Text, bibliography |
| Format | print, xiii, 106 leaves : ill. ; 30 cm. |
| Rights | Use of this resource is governed by the terms and conditions of the Creative Commons “Attribution-NonCommercial-NoDerivatives 4.0 International” License (http://creativecommons.org/licenses/by-nc-nd/4.0/) |
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