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Evaluating the use of a theory-based intervention to improve medication-taking behaviours: A Longitudinal mixed-methods study in patients with Pulmonary Arterial Hypertension. Applying Health Belief Model theory to understand patients’ medication and disease beliefs and using this to develop and evaluate targeted interventions delivered by a pharmacist to improve medication adherence

Pulmonary Arterial Hypertension (PAH) is a rare incurable condition affecting both the cardiac and respiratory systems. Patients living with PAH face the burden of both intensive medication regimens and debilitating disease symptoms. This study’s primary aim was to identify patients’ medication-taking behaviours and beliefs using a framework derived from the extended health belief model (EHBM), and to use this information to deliver personalised interventions to improve medication-taking behaviours. A
mixed-methodology longitudinal study design recorded patients’ parameters
over a 12-month period. Thirteen participants from Northern Ireland
completed the study. The results showed that the level of high-adherence to
PAH medicines, as assessed using the MARS questionnaire was 80%, but
this value differed when assessed via pill counting and interview data. There was a trend to improvement in observed and predicted medication adherence over the study duration. Participants’ beliefs showed a non-statistical increase in the specific-necessity beliefs and a reduction in
general-overuse belief. This study added to the EHBM new constructs of trust and support in being able to better predict nonadherent behaviours. Key medication-taking themes were self-confidence, perceived ranking of medicines, uncertainty and knowledge. This study developed important
learning that can be applied to future research on behavioural health studies. / Heart Trust Fund;
Actelion Pharmaceuticals

Identiferoai:union.ndltd.org:BRADFORD/oai:bradscholars.brad.ac.uk:10454/19218
Date January 2020
CreatorsJackson, Michael P.
ContributorsMorgan, Julie D., Quinn, Gemma L., Palmer, Timothy M.
PublisherUniversity of Bradford, Faculty of Life Sciences School of Pharmacy and Medical Sciences
Source SetsBradford Scholars
LanguageEnglish
Detected LanguageEnglish
TypeThesis, doctoral, PharmD
Rights<a rel="license" href="http://creativecommons.org/licenses/by-nc-nd/3.0/"><img alt="Creative Commons License" style="border-width:0" src="http://i.creativecommons.org/l/by-nc-nd/3.0/88x31.png" /></a><br />The University of Bradford theses are licenced under a <a rel="license" href="http://creativecommons.org/licenses/by-nc-nd/3.0/">Creative Commons Licence</a>.

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