In recent years mammary cancer has been increasingly recognized in pet rabbits.
In addition to uterine carcinomas—the most common tumor of female rabbits—mammary cancer can
also markedly reduce the life expectancy of pet rabbits. The aim of this review is to raise awareness
for these tumors and to report recent progress in related research. Their detailed characterization
will likely improve medical care for affected rabbits. Moreover, study results will contribute to
comparative pathology and may reveal if the rabbit is a suitable model for certain types of breast
cancer in humans. Available information suggests that most invasive cancer cases develop through
stepwise progression from non-invasive forms. Thus, early recognition will likely improve a complete
cancer cure. So far, the only treatment option is surgical excision and prognostic factors are unknown.
Recent investigations have identified tumor features with likely prognostic value. They have also
revealed differences and similarities to mammary tumors in other species and breast cancer in women.
Despite these initial data, continued research is necessary to gain more insights into the development
of these tumors and their molecular features.
| Identifer | oai:union.ndltd.org:DRESDEN/oai:qucosa:de:qucosa:84605 |
| Date | 06 April 2023 |
| Creators | Schöniger, Sandra, Degner, Sophie, Jasani, Bharat, Schoon, Heinz-Adolf |
| Publisher | MDPI |
| Source Sets | Hochschulschriftenserver (HSSS) der SLUB Dresden |
| Language | English |
| Detected Language | English |
| Type | info:eu-repo/semantics/publishedVersion, doc-type:article, info:eu-repo/semantics/article, doc-type:Text |
| Rights | info:eu-repo/semantics/openAccess |
| Relation | 2076-2615, 762 |
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