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Association between generalized anxiety levels and pain in a community sample: Evidence for diagnostic specificity

Background: It is unclear whether generalized anxiety disorder (GAD) has a specific relationship to pain syndromes, going beyond the established association of pain with anxiety syndromes in general.
Methods: Mental disorders were assessed in a community sample (N = 4181; 18–65 years) using the DSM-IV/M-CIDI. Several threshold definitions were used to define GAD and medically unexplained pain.
Results: The association between pain and GAD (odds ratio, OR = 5.8 pain symptoms; OR = 16.0 pain disorder) is stronger than the association between pain and other anxiety disorders (OR = 2.4 pain symptoms; OR = 4.0 pain disorder). This association extends to subthreshold level definitions of GAD with some indication for a non-linear dose–response relationship. The GAD-pain link cannot sufficiently be explained by demographic factors, comorbid mental or physical disorders.
Conclusions: The association of pain and generalized anxiety is not artifactual. Compared to other anxiety syndromes, it appears to be stronger and more specific suggesting the need to explore clinical and public health implications.

Identiferoai:union.ndltd.org:DRESDEN/oai:qucosa:de:qucosa:26835
Date January 2009
CreatorsBeesdo, Katja, Hoyer, Jürgen, Jacobi, Frank, Low, Nancy C.P., Höfler, Michael, Wittchen, Hans-Ulrich
PublisherTechnische Universität Dresden
Source SetsHochschulschriftenserver (HSSS) der SLUB Dresden
LanguageEnglish
Detected LanguageEnglish
Typedoc-type:article, info:eu-repo/semantics/article, doc-type:Text
SourceJournal of Anxiety Disorders, Bd. 23 (2009), Nr. 5, S. 684–693, ISSN: 0887-6185
Rightsinfo:eu-repo/semantics/openAccess
Relation10.1016/j.janxdis.2009.02.007

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