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Previous issue date: 2014-03-31 / Objective: Omentin is an adipokine expressed in visceral adipose tissue that has been associated with positive effects on metabolism. The objective of this study was to assess whether changes occur in circulating omentin levels and cardiovascular risk factors after abdominal subcutaneous liposuction with or without abdominoplasty. Materials and methods: Serum omentin levels and cardiovascular risk factors (blood pressure, lipid profile, and waist circumference) were assessed in 21 women at baseline and 8 to 12 weeks after abdominal liposuction with or without abdominoplasty. Weight, blood glucose levels, insulin levels, and the homeostasis model assessment (HOMA) index were also evaluated. Results: At 12-week follow-up, circulating omentin levels had not changed significantly from baseline (P = 0.11; effect size - ES = 0.37). Waist circumference was significantly decreased (P < 0.001; ES = -1.38). Blood pressure, lipid profile, blood glucose levels, insulin levels, and HOMA index were statistically unchanged. Conclusion: Abdominal subcutaneous liposuction, whether alone or with abdominoplasty, was not associated with significant changes in circulating omentin levels or cardiovascular risk factors / Objetivo: Omentina ? uma adipocina expressada no tecido adiposo visceral e associada a efeitos positivos sobre o metabolismo. Nosso objetivo foi avaliar se ocorre altera??o nos n?veis circulantes de omentina e em fatores de risco cardiovascular ap?s lipoaspira??o subcut?nea abdominal associada ou n?o ? abdominoplastia. Materiais e m?todos: N?veis s?ricos de omentina e fatores de risco cardiovascular, tais como: press?o arterial, perfil lip?dico e circunfer?ncia abdominal, foram avaliados em 21 mulheres antes e 8 a 12 semanas ap?s lipoaspira??o abdominal associada ou n?o ? abdominoplastia; peso, glicemia, insulina e ?ndice HOMA tamb?m foram estudados. Resultados: N?veis circulantes de omentina n?o se alteraram significativamente 12 semanas ap?s (P = 0,11; tamanho de efeito - E/S = 0,37); circunfer?ncia abdominal alterou significativamente (P<0,001; E/S = -1,38), enquanto outros fatores de risco cardiovascular, como press?o arterial e perfil lip?dico, n?o alteraram significativamente; glicemia, insulina e ?ndice HOMA tamb?m n?o alteraram significativamente. Conclus?o: Lipoaspira??o subcut?nea abdominal isolada, ou associada ? abdominoplastia, n?o levou a altera??es significativas nos n?veis de omentina nem em fatores associados ao aumento de risco cardiovascular
| Identifer | oai:union.ndltd.org:IBICT/oai:tede2.pucrs.br:tede/1763 |
| Date | 31 March 2014 |
| Creators | Lain, Fernanda Victorazzi |
| Contributors | Bodanese, Luiz Carlos |
| Publisher | Pontif?cia Universidade Cat?lica do Rio Grande do Sul, Programa de P?s-Gradua??o em Medicina e Ci?ncias da Sa?de, PUCRS, BR, Faculdade de Medicina |
| Source Sets | IBICT Brazilian ETDs |
| Language | Portuguese |
| Detected Language | English |
| Type | info:eu-repo/semantics/publishedVersion, info:eu-repo/semantics/masterThesis |
| Format | application/pdf |
| Source | reponame:Biblioteca Digital de Teses e Dissertações da PUC_RS, instname:Pontifícia Universidade Católica do Rio Grande do Sul, instacron:PUC_RS |
| Rights | info:eu-repo/semantics/openAccess |
| Relation | 7620745074616285884, 500, 600, -8624664729441623247 |
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