Yes / Purpose: To develop and validate the first patient-reported outcome measure (PROM)
to quantify vision-related dizziness. Dizziness is a common, multifactorial syndrome that
causes reductions in quality of life and is a major risk factor for falls, but the role of vision
is not well understood.
Methods: Potential domains and items were identified by literature review and discussions
with experts and patients to form a pilot PROM, which was completed by 335
patients with dizziness. Rasch analysis was used to determine the items with good
psychometric properties to include in a final PROM, to check undimensionality, differential
item functioning, and to convert ordinal questionnaire data into continuous interval
data. Validation of the final 25-item instrument was determined by its convergent validity,
patient, and item-separation reliability and unidimensionality using data from 223 patients
plus test–retest repeatability from 79 patients.
results: 120 items were originally identified, then subsequently reduced to 46 to form
a pilot PROM. Rasch analysis was used to reduce the number of items to 25 to produce
the vision-related dizziness or VRD-25. Two subscales of VRD-12-frequency and
VRD-13-severity were shown to be unidimensional, with good psychometric properties.
Convergent validity was shown by moderately good correlations with the Dizziness
Handicap Inventory (r = 0.75) and good test–retest repeatability with intra-class correlation
coefficients of 0.88.
conclusion: VRD-25 is the only PROM developed to date to assess vision-related
dizziness. It has been developed using Rasch analysis and provides a PROM for this
under-researched area and for clinical trials of interventions to reduce vision-related
dizziness. / College of Optometrists (UK) research studentship.
| Identifer | oai:union.ndltd.org:BRADFORD/oai:bradscholars.brad.ac.uk:10454/17160 |
| Date | 29 May 2018 |
| Creators | Armstrong, Deborah, Alderson, Alison J., Davey, Christopher J., Elliott, David |
| Source Sets | Bradford Scholars |
| Language | English |
| Detected Language | English |
| Type | Article, Published version |
| Rights | © 2018 Armstrong, Alderson, Davey and Elliott. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms., CC-BY |
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