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Previous issue date: 2016-08-29 / As neoplasias representam a segunda causa de morte no mundo. Entre elas, o c?ncer
de pulm?o destaca-se como o mais comum de todos os tumores malignos e uma das
principais causas de mortalidade entre homens e mulheres nos pa?ses desenvolvidos.
O objetivo deste trabalho ? analisar a tend?ncia de mortalidade por c?ncer de pulm?o
no per?odo de 1998 a 2012 e realizar proje??o da taxa de mortalidade at? o ano de
2032. Trata-se de um estudo ecol?gico do tipo misto que avaliou a taxa de mortalidade
por c?ncer de pulm?o observando a faixa et?ria da popula??o, assim como o local de
resid?ncia desses ?bitos considerando uma s?rie hist?rica de 15 anos. As proje??es de
cada per?odo foram calculadas utilizando o modelo idade ? per?odo ? coorte do
programa Nordpred, no software R. A an?lise de tend?ncia de mortalidade foi realizada
por meio do software Joinpoint Regression Program. Foi utilizado o Annual Percentage
Change (APC) para avaliar a tend?ncia de cada seguimento analisado e estimando os
valores estatisticamente significativos considerando um n?vel de confian?a de 95%.
Ademais, avaliou se altera??es no n?mero de mortes est?o relacionadas ? popula??o
ou ao risco de desenvolver o c?ncer de pulm?o. No Brasil 2.237.346 ?bitos foram
decorrentes de neoplasia no per?odo de 1? de janeiro de 1998 a 31 de dezembro de
2012 e 273.357 (12,21%) foram por c?ncer de pulm?o. A faixa et?ria com maior n?mero
de ?bitos, tanto em homens quanto em mulheres, foi a compreendida pelos indiv?duos
com idade maior ou igual a 60 anos. A an?lise por meio de Joinpoint apontou redu??o
significativa na taxa de mortalidade padronizada para todo o territ?rio brasileiro, assim
como em todas as regi?es para os homens. Para as mulheres, a regi?o Norte
apresentou tend?ncia ? estabilidade com posterior joinpoint em 2015 e tend?ncia ?
redu??o significativa. Mas, a an?lise revelou que tanto para o Brasil quanto para as
demais regi?es, com exce??o da regi?o Norte, houve tend?ncia de aumento
significativo e presen?a de joinpoint com posterior per?odo de estabilidade. Contudo,
essas mudan?as em homens e mulheres estar?o relacionadas ao tamanho ou ?s
mudan?as estrutura et?ria da popula??o. Conclui-se que no per?odo investigado,
considerando homens e mulheres, haver? diferen?as na mortalidade por c?ncer de
pulm?o no Brasil e nas regi?es brasileiras. E, entre outros fatores, essa mudan?a ter?
rela??o com o tamanho e a faixa et?ria da popula??o investigada. / Neoplasms represent the second cause of death worldwide. Among them, lung cancer
stands out as the most common of all malignant tumors and a major cause of death
among men and women in developed countries. The aim of this study is to analyze the
trend of mortality from lung cancer from 1998 to 2012 and to realize prediction of
mortality by the year 2032. This is an ecological study of mixed type that evaluated the
mortality rate lung cancer noting the age of the population, as well as the place of
residence of these deaths considering a historical series of 15 years. The predictions of
each period were calculated using the model age - period - cohort Nordpred program in
software R. The mortality trend analysis was performed using the Joinpoint Regression
Program software. The Annual Percentage Chance (APC) was used to assess the trend
of each segment analyzed and estimating statistically significant values considering a
95% confidence level. In addition, we evaluated whether changes in the number of
deaths are related to the population or the risk of developing lung cancer. In Brazil
2,237,346 deaths were due to cancer in the period from January 1 1998 to December
31, 2012 and 273,357 (12.21%) were from lung cancer. The age group with the highest
number of deaths in both men and women, was understood by persons aged greater
than or equal to 60 years. The analysis by Joinpoint showed significant reduction in the
standardized mortality rate for the entire Brazilian territory, as well as in all regions for
men. For women, the North tended to stability with subsequent joinpoint in 2015 and a
significant reduction trend. But the analysis revealed that both Brazil and to other
regions, except the North, there was a trend of significant increase and presence of
joinpoint with subsequent period of stability. However, these changes in men and
women will be related to the size or to change the age of the population. We conclude
that in the period investigated, considering men and women, there will be differences in
mortality from lung cancer in Brazil and the Brazilian regions. And, among other factors,
this change will have regard to the size and age of the study population.
| Identifer | oai:union.ndltd.org:IBICT/oai:repositorio.ufrn.br:123456789/22156 |
| Date | 29 August 2016 |
| Creators | Barbosa, Maria Helena Pires Ara?jo |
| Contributors | 00902557475, http://lattes.cnpq.br/9953301230987878, Barbosa, Isabelle Ribeiro, 00953152413, http://lattes.cnpq.br/0211762022010569, Cancela, Marianna de Camargo, 01935141929, http://lattes.cnpq.br/7515982754589252, Souza, Dyego Leandro Bezerra de |
| Publisher | PROGRAMA DE P?S-GRADUA??O EM SA?DE COLETIVA, UFRN, Brasil |
| Source Sets | IBICT Brazilian ETDs |
| Language | Portuguese |
| Detected Language | English |
| Type | info:eu-repo/semantics/publishedVersion, info:eu-repo/semantics/masterThesis |
| Source | reponame:Repositório Institucional da UFRN, instname:Universidade Federal do Rio Grande do Norte, instacron:UFRN |
| Rights | info:eu-repo/semantics/openAccess |
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