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Previous issue date: 2014-08-06 / Purpose: The pharyngeal airway may change after mandibular advancement in patient using intraoral device in obstructive sleep apnea (OSA) treatment. The aim of this study was to evaluate the dimensional and volumetric changes of superior airway promoted by an adjustable mandibular advancement device (AMAD) and the polysomnographic results in patients with OSA facial pattern facial Cl II.
Materials and Methods: The present prospective study selected 11 patients with OSA (5 males and 6 females) and radiographs and ct scans, and polysomnographic exam were performed with and without the use of AMAD. The airway was assessed in the following aspects: superior pharyngeal space (S1), posterior palatal space (S2), median pharyngeal space (S3), posterior pharyngeal space (S4), inferior pharyngeal space (S5), pharyngeal volume (CT1), anterior-posterior lengths of the smallest cross-sectional area (CT2), lateral lengths of smallest cross-sectional area (CT3), pharyngeal smallest cross-section area (CT4). The analyzed variables of the polysomnographic data were: AH total (total number of apnea and hypopnea), AHI (apnea and hypopnea index - calculated as the average number of respiratory events per hour of sleep); AI (Apnea index), HI (Hypopnea index), Apnea duration, Hypopnea duration, Lowest O2% saturation.
Results: The use of the AMAD induced an insignificant decrease of the pharyngeal airway as observed in the S1 (20.091 to 20.01mm decrease of -0,26%) and S4 (11.08 to 10.59mm decrease of -4.2%). A not statistically significant increase was observed in S2 (8.33 to 9.43mm increase of 13.67%), S3 (18.23 to 18.34mm increase of 1,2%) and CT1 (13393 to 15948 mm3 increase of 19,07%). Statistically significant increases were observed in S5 (11.92 to 15.67mm increase of 47.08%), CT2 (media of 5.81 to 7,71mm increase of 32,7%), CT3 (17,3 mm to 22,33 mm increase of 29.07%) and CT4 (79,77 to 119,38 mm2 increase of 49.65%), and determined a significant decrease of the variables total AH (159,9 to 54,8 reduction of 34,27%), AHI (21,57 to 7,54 decrease of 34.95%) and AI (17,33 to 3,99 reduction 23,1%). A nonsignificant reduction in the duration of apnea (16,4 to 14,7 reduction of 10.36%), Hypopnea (18.42 to 16,94 reduction of 8.03%). A nonsignificant increase of HI (3.26 to 3.29 increase of 0.92%), Lowest O2% saturation (76.6 to 82.9 increase of 8.22%).
Conclusions: A correlation between the mandibular advancement and changes in the measurements of pharyngeal airway were significant with the use of AMAD in the inferior pharyngeal space (S5), anterior posterior lengths of smallest pharyngeal cross-sectional area (CT2), lateral lengths of smallest pharyngeal cross-sectional area (CT3), and pharyngeal smallest cross-section area (CT4), and polysomnographic data showed a significant improvement with the reduction of the variables AH total, AHI, HI. Results showed that the use of the AMAD allows an increase of the superior airway and improves important variables of the polysomnography exam, being the lateral teleradiography, CT scan and polysomnography are effective methods for the diagnosis and evaluation of the treatment s progress. / Objetivo: A via a?rea faringiana pode mudar ap?s o avan?o mandibular promovido por aparelhos intra-orais para o tratamento de apn?ia obstrutiva do sono (OSA). O objetivo deste estudo foi avaliar as altera??es dimensionais e volum?tricas da via a?rea superior promovida pelo o uso de um aparelho intra-oral ajust?vel de avan?o mandibular (AMAD) bem como os resultados polissonograficos em pacientes com OSA padr?o facial Cl II. Materiais e M?todos: O estudo prospectivo selecionou 11 pacientes (5 homens e 6 mulheres) sendo realizados telerradiografias de perfil, tomografias computadorizadas, e exame polissonografico com e sem o uso do AMAD. A via a?rea foi avaliada nos seguintes aspectos: espa?o faringeano superior (S1), espa?o palatal posterior (S2), espa?o faringiano m?dio (S3), espa?o faringiano posterior (S4), espa?o faringiano inferior (S5), volume faringiano (CT1), di?metro antero-posterior da menor ?rea de sec??o faringeana (CT2), dimens?o lateral da menor ?rea de sec??o far?ngea (CT3), ?rea de menor sec??o faringiana transversal (CT4), e os exames polissonogr?ficos foram avaliados as vari?veis AH total (numero total de apn?ias e hipoapn?ias), AHI (?ndice de apn?ia e hipoapn?ia), AI (?ndice de apn?ia), HI (?ndice de hipoapn?ia), dura??o de apn?ia, dura??o de hipoapn?ia, menor satura??o O2%. Resultados: O uso do AMAD gerou uma redu??o da via a?rea faringiana n?o significativa observada em S1 (20.091 para 20.01mm - diminui??o de -0,26%) e S4 (11.08 para 10.59mm - diminui??o de -4.2%). Um aumento estatisticamente n?o significante foi observado em S2 (8.33 para 9.43mm - aumento de 13.67%), S3 (18.23 para 18.34mm - aumento de 1.2%) e CT1 (13393 para 15948 mm3 aumento de 19.07%). Um aumento estatisticamente significante foi observado em S5 (11.92 para 15.67mm aumento de 47.08%), CT2 (5.81 para 7.71mm aumento de 32.7%), CT3 (17,3 mm para 22,33mm - aumento de 29.07%) e CT4 (79,77 para 119,38 mm2 aumento de 49.65%), e determinou uma diminui??o significativa das vari?veis AH total (159.9 para 54.8 redu??o de 34.27%), AHI (21.57 para 7.54 redu??o de 34.95%) e Al (17.33 para 3.99 redu??o de 23.1%). Uma redu??o n?o significativa da dura??o de apn?ia (16,4 para 14,7 redu??o de 10,36%), hipoapn?ia (18,42 para 16,94 redu??o de 8,03%). Um aumento n?o significativo do HI (3,26 para 3,29 aumento de 0,92%), menor satura??o de O2% (76,6 para 82,9 aumento de 8,22%). Conclus?es: A rela??o entre o movimento de avan?o mandibular e as altera??es das medidas da via a?rea faringiana foram observadas de forma significativa com o uso do AMAD nos espa?o faringiano inferior (S5), dimens?o antero-posterior da ?rea de menor sec??o transversa da faringe (CT2), dimens?o lateral da ?rea de menor sec??o transversa da faringe (CT3), e ?rea de menor secc?o transversa (CT4), bem como os dados polissonogr?ficos demonstraram uma melhora significativa com a redu??o das vari?veis AH total, AHI, e HI. Os resultados demonstraram que o uso do AMAD promove um aumento da via a?rea superior e melhora vari?veis importantes do exame polissonogr?fico, sendo a a teleradiografia lateral, tomografia computadorizada e a polissonografia m?todos eficazes para o diagn?stico e evolu??o do progresso dos tratamentos.
| Identifer | oai:union.ndltd.org:IBICT/oai:tede2.pucrs.br:tede/1269 |
| Date | 06 August 2014 |
| Creators | Woltmann, Marcus |
| Contributors | Oliveira, Rog?rio Belle de |
| Publisher | Pontif?cia Universidade Cat?lica do Rio Grande do Sul, Programa de P?s-Gradua??o em Odontologia, PUCRS, BR, Faculdade de Odontologia |
| Source Sets | IBICT Brazilian ETDs |
| Language | Portuguese |
| Detected Language | English |
| Type | info:eu-repo/semantics/publishedVersion, info:eu-repo/semantics/doctoralThesis |
| Format | application/pdf |
| Source | reponame:Biblioteca Digital de Teses e Dissertações da PUC_RS, instname:Pontifícia Universidade Católica do Rio Grande do Sul, instacron:PUC_RS |
| Rights | info:eu-repo/semantics/openAccess |
| Relation | -8096554818733665164, 500, 600, 4673435736271820140 |
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