Return to search

Synthesis of Isoguvacine, Paroxetine and Pseudoheliotridane

Carbon skeleton of polysubstituted pyroglutamates with three contiguous asymmetric centers was built up in one base-induced coupling/cyclization reaction of £\-sulfonylacetamide with 2-bromo-2-propenoates and has been used as the key step in the formal synthesis of isoguvacine paroxetine, and psudoheliotridane.

Identiferoai:union.ndltd.org:NSYSU/oai:NSYSU:etd-0819105-140357
Date19 August 2005
CreatorsTseng, Tze-Wei
ContributorsMeng-Yang Chang, Cherng-Chyi Tzeng, Nein-Chen Chang, Chin-Hsing Chou
PublisherNSYSU
Source SetsNSYSU Electronic Thesis and Dissertation Archive
LanguageCholon
Detected LanguageEnglish
Typetext
Formatapplication/pdf
Sourcehttp://etd.lib.nsysu.edu.tw/ETD-db/ETD-search/view_etd?URN=etd-0819105-140357
Rightsrestricted, Copyright information available at source archive

Page generated in 0.0022 seconds