Thiabendazole, the most commonly used drug to treat strongyloidiasis, has many side effects and high relapse rates. Ivermectin is an effective antiparasitic drug that could be used in the treatment of this disease. Sixteen patients with proven strongyloidiasis were randomized to receive either 1 dose of ivermectin 200 mg/kg; ivermectin 200 mg/kg/day for 2 days; or thiabendazole 25 mg/kg twice a day for 3 days. Nine patients (total) received ivermectin and 7 received thiabendazole. Two relapses occurred in the thiabendazole group. All side effects were seen only in this group. Ivermectin may be a better tolerated, more effective treatment for strongyloidiasis.
| Identifer | oai:union.ndltd.org:ETSU/oai:dc.etsu.edu:etsu-works-12334 |
| Date | 06 May 1994 |
| Creators | Salazar, S. A., Berk, S. H., Howe, D., Berk, S. L. |
| Publisher | Digital Commons @ East Tennessee State University |
| Source Sets | East Tennessee State University |
| Detected Language | English |
| Type | text |
| Source | ETSU Faculty Works |
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