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Umbilical cord arterial 8-iso-prostaglandin F2α concentrations in pregnancies complicated by meconium stained liquor.

Liu Bao Yi. / Thesis (M.Phil.)--Chinese University of Hong Kong, 2004. / Includes bibliographical references (leaves 83-104). / Abstracts in English and Chinese. / ABSTRACT --- p.i / ACKNOWLEDGEMENT --- p.v / TABLE OF CONTENTS --- p.vi / LIST OF ABBREVIATIONS --- p.xii / LIST OF FIGURES --- p.xivv / LIST OF TABLES --- p.xv / PUBLICATION RELATED TO THIS THESIS --- p.xvii / Chapter PART 1 --- INTRODUCTION AND LITERATURE RESEARCH / Chapter CHAPTER 1 --- INTRODUCTION --- p.1 / Chapter CHAPTER 2 --- MECONIUM STAINED LIQUOR --- p.3 / Chapter 2.1 --- AMNIOTIC FLUID --- p.3 / Chapter 2.1.1 --- Function of Amniotic Fluid --- p.3 / Chapter 2.1.2 --- Composition Of Amniotic Fluid --- p.3 / Chapter 2.1.3 --- Regulation Of Amniotic Fluid --- p.4 / Chapter 2.1.4 --- Abnormality Of Amniotic Fluid Volume --- p.4 / Chapter 2.2 --- MECONIUM STAINED LIQUOR --- p.6 / Chapter 2.2.1 --- Formation And Composition Of Meconium --- p.6 / Chapter 2.2.2 --- Peristalsis Of Fetal Gastrointestinal Tract --- p.7 / Chapter 2.2.3 --- Meconium Stained Liquor(MSL) --- p.7 / Chapter 2.2.3.1 --- Maturation Theory --- p.7 / Chapter 2.2.3.2 --- Cord Compression Theory --- p.9 / Chapter 2.2.3.3 --- Fetal Hypoxia Theory --- p.10 / Chapter 2.2.4 --- Fetal Effect Of Meconium In Amniotic Cavity --- p.11 / Chapter 2.2.5 --- Meconium Aspiration Syndrome --- p.12 / Chapter 2.2.6 --- Clinical Significance And Limitation Of Studies --- p.13 / Chapter 2.3 --- Purpose Of Study --- p.14 / Chapter CHAPTER 3 --- OXIDATIVE STRESS AND FETAL HYPOXIA --- p.16 / Chapter 3.1 --- OXIDATIVE STRESS --- p.16 / Chapter 3.2 --- FREE RADICALS --- p.16 / Chapter 3.2.1 --- Sources Of Free Radicals --- p.17 / Chapter 3.2.1.1 --- Biological Source Of Free Radicals --- p.17 / Chapter 3.2.1.2 --- Intracellular Source Of Free Radicals --- p.17 / Chapter 3.2.1.3 --- Composition Of Free Radicals And Reactive Oxygen Species --- p.18 / Chapter 3.2.2 --- Cellular Components At Risk From Free Radicals Damage --- p.20 / Chapter 3.2.2.1 --- Proteins --- p.20 / Chapter 3.2.2.2 --- Nucleic Acids And DNA --- p.21 / Chapter 3.2.2.3 --- Membrane Lipids --- p.21 / Chapter 3.2.3 --- Lipid Peroxidation --- p.21 / Chapter 3.2.3.1 --- Chemical Substances Of Membranes --- p.21 / Chapter 3.2.3.2 --- The Reactions Of Lipid Peroxidation --- p.22 / Chapter 3.2.3.3 --- Lipid Peroxidation In Pregnancy --- p.23 / Chapter 3.2.4 --- Protection Against Lipid Peroxidation --- p.24 / Chapter 3.2.5 --- Isoprostanes --- p.26 / Chapter 3.2.5.1 --- Definition --- p.26 / Chapter 3.2.5.2 --- Formation Of Isoprostanes --- p.26 / Chapter 3.2.5.3 --- Metabolism Of Isoprostanes --- p.27 / Chapter 3.2.5.4 --- Biological Characteristics Of Isoprostanes --- p.29 / Chapter 3.2.5.5 --- Isoprostanes As Mediators Of Oxidantive Stress --- p.29 / Chapter 3.3 --- FETAL HYPOXIA --- p.30 / Chapter 3.3.1 --- Fetal Metabolism And Energy Supply --- p.30 / Chapter 3.3.2 --- Free Radical Generation And Fetal Hypoxia-Reoxygenation --- p.33 / Chapter 3.3.3 --- Fetal Hypoxia And Fetal Brain Injury --- p.34 / Chapter 3.3.4 --- Measurement Of Fetal Hypoxia --- p.35 / Chapter 3.3.4.1 --- Acid-Base Balance --- p.35 / Chapter 3.3.4.2 --- Fetal Heart Rate Monitoring --- p.36 / Chapter 3.3.4.3 --- Apgar scores --- p.37 / Chapter 3.3.4.4 --- Pulse Oximetry --- p.37 / Chapter 3.3.4.5 --- Lipid Peroxides --- p.38 / Chapter CHAPTER 4 --- AMNIOINFUSION --- p.40 / Chapter 4.1 --- AMNIOINFUSION --- p.40 / Chapter 4.2 --- AMNIOINFUSION FOR OLIGOHYDRAMNIOS --- p.40 / Chapter 4.3 --- AMNIOINFUSION FOR MECONIUM STAINED LIQUOR --- p.41 / Chapter 4.4 --- PURPOSE OF THE STUDY --- p.42 / Chapter PART 2 --- CLINICAL PROTOCOLS AND MEASUREMENT OF ISOPROSTANES / Chapter CHAPTER 5 --- CLINICAL PROTOCOLS --- p.43 / Chapter 5.1 --- ETHICS --- p.43 / Chapter 5.2 --- CLINICAL PROTOCOLS --- p.43 / Chapter 5.2.1 --- Artificial Rupture Of Membranes (Amniotomy) --- p.43 / Chapter 5.2.2 --- Classification of Meconium Stained Liquor --- p.44 / Chapter 5.2.3 --- Electronic Fetal Heart Rate Monitoring --- p.44 / Chapter 5.2.4 --- Monitoring The Progress of Labour --- p.44 / Chapter 5.2.5 --- Umbilical Cord Blood Gas Analysis --- p.45 / Chapter 5.2.6 --- Apgar Score --- p.45 / Chapter 5.2.7 --- Meconium Aspiration --- p.46 / Chapter 5.2.8 --- Clinical Outcome --- p.46 / Chapter CHAPTER 6 --- MEASUREMENT OF ISOPROSTANES --- p.50 / Chapter 6.1 --- BLOOD PREPARATION --- p.50 / Chapter 6.2 --- REAGENTS --- p.50 / Chapter 6.3 --- GAS CHROMATOGRAPHY AND MASS SPECTROMETRY (GC-MS) --- p.51 / Chapter 6.4 --- PROCEDURES --- p.51 / Chapter 6.5 --- DATA RELIABILITY --- p.53 / Chapter PART 3 --- RESULTS AND DISCUSSION / Chapter CHAPTER 7 --- MECONIUM STAINED LIQUOR (MSL) DURING LABOUR AND NEONATAL CORD BLOOD 8-IS〇-PGF2α CONCENTRATION --- p.54 / Chapter 7.1 --- OBJECTIVE --- p.54 / Chapter 7.2 --- MATERIALS AND METHOD --- p.55 / Chapter 7.3 --- STATISTICAL ANALYSIS --- p.56 / Chapter 7.4 --- RESULTS --- p.57 / Chapter 7.5 --- DISCUSSION --- p.65 / Chapter 7.6 --- CONCLUSION --- p.67 / Chapter CHAPTER 8 --- EVALUATION OF PROPHYLACTIC AMNIOINFUSION FOR INTRAPARTUM MECONIUM STAINED LIQUOR --- p.69 / Chapter 8.1 --- OBJECTIVE --- p.69 / Chapter 8.2 --- MATERIALS AND METHOD --- p.69 / Chapter 8.2.1 --- Study Group: 226}0ب MSL+AI' --- p.69 / Chapter 8.2.2 --- The Procedure Of Amnioinfusion --- p.70 / Chapter 8.2.3 --- Other Study Group --- p.71 / Chapter 8.3 --- STATISTIC ANALYSIS --- p.71 / Chapter 8.4 --- RESULTS --- p.72 / Chapter 8.4.1 --- Comparison Between The 'MSL+AI' And 'MSL-AI' Groups --- p.72 / Chapter 8.4.2 --- Comparison Between 226}0بMSL+AI'And 'Clear Liquor' Groups --- p.74 / Chapter 8.5 --- DISCUSSION --- p.77 / Chapter 8.6 --- CONCLUSION --- p.79 / Chapter CHAPTER 9 --- COMMENTS AND FUTURE RESEARCH --- p.80 / BIBLIOGRAPHY --- p.83

Identiferoai:union.ndltd.org:cuhk.edu.hk/oai:cuhk-dr:cuhk_324846
Date January 2004
ContributorsLiu, Bao Yi., Chinese University of Hong Kong Graduate School. Division of Obstetrics and Gynaecology.
Source SetsThe Chinese University of Hong Kong
LanguageEnglish, Chinese
Detected LanguageEnglish
TypeText, bibliography
Formatprint, xvi, 104 leaves : ill. ; 30 cm.
RightsUse of this resource is governed by the terms and conditions of the Creative Commons “Attribution-NonCommercial-NoDerivatives 4.0 International” License (http://creativecommons.org/licenses/by-nc-nd/4.0/)

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