Background: Periodontal disease has been associated with gestational complications
and both conditions have a high prevalence in rural populations from developing regions.
A cross-sectional study was carried out to explore the relationship between periodontal
inflamed surface area (PISA), blood pressure (BP), and, serum uric acid levels (UA) in a
group of rural North Chinese pregnant women in the third trimester of pregnancy.
Methods: Three hundred and thirty-five rural women aged 20–34 years, with normal
body mass index (BMI) were examined in a cross-sectional study during their third
trimester of gestation. Exclusion criteria were history of pregnancy complications,multiple
pregnancy, smoking habits, diabetes, hypertension or any known infectious disease.
Socio-demographic variables, including age and socioeconomic status (SES), systolic
blood pressure (SBP) and diastolic blood pressure (DBP) readings, serum UA levels,
and PISA values were recorded. A structural equation model was implemented with two
constructed latent variables including “Dem” (comprising of age and SES category to
represent unobserved demographic variables) and, “BP” (comprising of SBP and DBP to
account for measurement error and lack of multiple BP readings). The model accounted
for co-variance of BP and UA, and implemented simultaneous regressions for BP and
UA as outcomes, upon Dem and PISA values as exogenous variables.
Results: The median PISA score was 1,081.7 (IQR = 835.01), reflecting high levels of
periodontal inflammation in the sample. SEM showed a significant association of PISA
with BP (estimate = 0.011, 95%CI = 0.009–0.012 p < 0.001) and UA (estimate = 0.001,
95% CI = 0.001–0.001, p < 0.001).
Conclusion: Higher PISA values were significantly associated with higher blood
pressure and uric acid levels among rural pregnant women in a cross-sectional sample
from a center in North China after accounting for a latent demographic construct derived
from age and SES.
| Identifer | oai:union.ndltd.org:DRESDEN/oai:qucosa:de:qucosa:84552 |
| Date | 04 April 2023 |
| Creators | Hu, Shaonan, Yu, Feifan, Jiang, Hong, Shang, Wei, Miao, Hui, Li, Simin, Zhao, Jianjiang, Xiao, Hui |
| Publisher | Frontiers Research Foundation |
| Source Sets | Hochschulschriftenserver (HSSS) der SLUB Dresden |
| Language | English |
| Detected Language | English |
| Type | info:eu-repo/semantics/publishedVersion, doc-type:article, info:eu-repo/semantics/article, doc-type:Text |
| Rights | info:eu-repo/semantics/openAccess |
| Relation | 2297-055X, 830732 |
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