Includes bibliographical references (leaves 190-238). / Bacille Calmette-Guerin (BCG), the only currently available tuberculosis vaccine, is the most widely administered vaccine in the Expanded Programme on Immunisation (EPI). Despite this, many gaps in our knowledge of BCG-induced T cell responses exist. The primary objective of this study was to comprehensively delineate T cell immunity induced by BCG vaccination of newborns and to longitudinally assess BCG-specific T cell responses over the first year of life.
Identifer | oai:union.ndltd.org:netd.ac.za/oai:union.ndltd.org:uct/oai:localhost:11427/14310 |
Date | January 2011 |
Creators | Soares, Andreia |
Contributors | Hanekom, Willem A |
Publisher | University of Cape Town, Faculty of Health Sciences, Department of Paediatrics and Child Health |
Source Sets | South African National ETD Portal |
Language | English |
Detected Language | English |
Type | Doctoral Thesis, Doctoral, PhD |
Format | application/pdf |
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